In recent years,the hydrogel-based tissue adhesives have been extensively investigated for their excellent biocompatibil......

A dual-switch-controlled release system was developed to treat inflammation....

In recent decades,various kinds of nanomaterials have been widely investigated as potential therapeutic agents for cance......

In recent years,multifunctional nanoparticles have received considerable attention in many applications such as biosenso......

In the quest to treat intracellular infectious diseases and virus infection,nanoparticles(NPs)have been considered to be......

Stimulative-responsible targeted drug delivery systems is important in the development of anti-cancer drug delivery appl......

Nanoscale building elements are crucial for the design of theranostic platforms that simultaneously detect and treat dis......

Accurate diagnosis of tumors and their pathological states could effectively improve the therapeutic outcomes.Magnetic r......

Ortho ester-based pH-responsive polymeric micelles have drawn much interest for delivery of antitumor drugs due to the p......

Photodynamic therapy(PDT)is an attractive minimal-invasive modality for cancer treatment [1].Upon excitation by light,th......

Design and development of multi-component polymer materials for controlled drug release has become a subject of great in......

Synthetic polypeptides inherit many intriguing properties of proteins such as excellent biocompatibility,biodegradabilit......

Photodynamic therapy (PDT) has exhibited a great potential in cancer therapy due to its noninvasive and effective proper......

In the quest to treat intracellular infectious diseases and virus infection,nanoparticles (NPs) have been considered to ......

Mesoporous silica nanoparticles (MSN) have been intensively studied for drug delivery owing to their outstanding physico......

Photodynamic therapy (PDT),has been widely concerned in recent years for cancer therapy.Among the existing NIR dyes,BODI......

Biofilms which contribute to the persistent bacterial infections pose a serious threat to global public health,mainly du......

Chemotherapy plays an important role in the treatment of cancer,but the optimal clinical approach for chemotherapy has n......

In the past decades,supramolecular host-guest chemistry has gained increasing interests in constructing smart polymeric ......

Cancer is still the main threat to human health.As compared with chemotherapy and radiation therapy,synergistic therapy ......

A series of novel and biocompatible hyperbranched polyglycidol-b-poly(L-lactide) (HBP-b-p(L-lactide)n) (n =10,20,30 and ......

Multifunctional theranostics have recently been intensively explored to optimize the efficacy and safety of the therapeu......

Poly(ethylene glycol) (PEG) with good biocompatibility and resistance to protein adsorption is the commonly used hydroph......

Polymeric micelles have recently received great attention as a promising vehicle for drug delivery.Generally,both the wa......

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In order to weaken the toxic side effects of the antitumor drugs in normal tissues to the utmost extent,various pH stimu......

The combination integration of diagnostic and therapeutic functionalities into one system generates theranostic platform......

Developing tumor-targeting drug delivery system with enhanced tumor retention,and efficient intracellular drug release i......

Objective To explore the synthetic method of a nanomicelle(sericin-PBLG-DOX),and the mechanism of reversing cancer drug ......

Objectives: A novel pH-and redox-responsive nanoparticle system was designed based on charge reversible pullulan derivat......

Cancer therapy by employing synthetic materials as delivery carriers has made great progress in recent decades.However,t......

Purpose: To synthesize pH-responsive single-walled carbon nanotubes (SWCNTs) loading survivin siRNA, and to characterize......

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Purpose: To obtain a pH-responsive Doxorubicin drug delivery system.Methods: A novel and well-defined pH-triggered backb......

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In this study,a graphene oxide(GO)-polyethylenimine(PEI)-polyethylene glycol(PEG)graft copolymer wassynthesized.DOX load......

pH- and photo-dual-response self-assembled structures were fabricated from the carboxylic-substituted azobenzene derivat......

　　In the quest to treat intracellular infectious diseases and virus infection,nanoparticles(NPs)have been considered t......

　　Double-walled polymeric hollow spheres(dPHSs)with independent temperature and pH-responsiveness in each shell have a......

To improve therapeutic effect and reduce severely side effects of carboplatin(CBP),the gas-generating nanocapsules were ......

Optomagnetic multifunctional composite has attracted much attention in recent years because of its promising application......

Functionalization of mesoporous silica spheres with well-dispersed and ultra-small nanodots to exert their synergistic e......

Immune vaccination is a critically important strategy in disease prevention and treatment.In vaccination,ef-ficient vacc......

In this work,zwitterionic polymer(polyzwitterion)coated nanodiamonds(ND)with tumorous pH responsiveness were prepared fo......

pH响应型聚合物前药作为新兴的递药系统具有良好的应用前景。它能够主动靶向于肿瘤细胞,实现细胞内药物的可控释放,增强药物疗效并......

Owing to the low pH value in tumor and cancer cells,drug delivery systems based on pH-responsive polymer nanocarriers ha......

Smart nanoparticles that respond to pathophysiological parameters,such as pH,GSH,and H2O2,have been developed with the h......

Since the discovery that nano-scaled particulates can easily be incorporated into tumors via the enhanced permeability a......

四(4-苯乙烯基)硅烷(TVBS)和溴代二苯乙烯基吡啶(Br-DSP)通过Heck偶联反应构筑以共价键连接的具有pH响应的新型多孔材料.材料具有......