PATHOGENESIS相关论文
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近年来，自身免疫性肝炎病例数在全世界范围内均呈明显上升趋势，但其病因及发病机制仍不明确，目前普遍认为是由于机体免疫调节紊乱导致......
Are ATXN2 variants modifying our understanding about neural pathogenesis, phenotypes, and diagnostic
ATXN2 one gene with multiple phenotype effects: ATXN2 gene encodes a cytosolic protein (ataxin-2) with pleiotropic funct......
结直肠侧向发育型肿瘤(laterally spreading tumor，LST)是一种特殊形态学的大肠表浅性肿瘤，LST的病变形态及发生、发展规律不同于一......
2019新型冠状病毒(2019 novel coronavirus，2019-nCoV)的主要靶器官是肺，严重者发生急性呼吸窘迫综合征而危及生命。2019-nCoV的人类......
Coronavirus disease 2019 (COVID-19),caused by severe acute respiratory syndrome coronavirus 2,is a major public health i......
Integrating 16S sequencing and metabolomics study on anti-rheumatic mechanisms against collagen-indu
Wantong Jingu Tablet(WJT),a mixture of traditional Chinese medicine,was reported to relieve the symptoms of rheumatoid a......
肺肠型腺癌是原发性肺腺癌的罕见病理亚型，指肺腺癌中肠型分化成分超过50%者，因其与结直肠腺癌在形态学及免疫组化特征方面有某些共......
巨型先天性黑色素细胞痣简称巨痣，是一种罕见的先天畸形，以病变面积巨大的先天性黑色素细胞痣为特征，呈黑、褐色外观，可伴有毛发生长、......
支气管哮喘(哮喘)是一种以不同程度的气流阻塞、气道高反应性和气道炎症为特点的复杂炎症性疾病。线粒体损伤及功能障碍是哮喘重要......
银屑病是一种免疫介导的多因素炎症性皮肤病，以表皮角质形成细胞异常增殖、毛细血管扩张、中性粒细胞浸润为主要病理表现。磷脂酰肌......
慢性心力衰竭是各种心血管疾病的终末阶段，是我国老年人的常见病之一。肌少症是一种与年龄相关的骨骼肌数量或质量的丧失以及肌肉力......
泪囊炎是眼科的常见病和多发病，临床治疗主要是通过手术摒弃阻塞的鼻泪管，在鼻腔内开放新的泪液引流通路。现阶段，对其发病机制的认识......
本次年鉴主要介绍趋化因子及受体的作用、氧化应激的参与过程、脑脊液蛋白质组学以及神经影像学在原发性三叉神经痛发病机制上的研......
本年鉴总结带状疱疹后神经痛发病机制研究，包括单核苷酸多态性、髓鞘碱性蛋白、KCNA2-AS、BDNF/TrkB.T1以及细胞钙紊乱与带状疱疹后......
Recent progress in understanding the role of genes in the pathogenesis of cutaneous squamous cell ca
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin tumor in humans. Ultraviolet (UV) radiation is a......
Some stress response-related genes have been identified in Ustilaginoidea virens, but it is not clear whether and how de......
Liver failure is a serious liver damage caused by many factors, leading to severe impairment or decompensation of synthe......
剥脱性青光眼是继发于剥脱综合征的一种青光眼类型。近年来，国内外学者对剥脱性青光眼的发病机制和危险因素进行了大量研究，发现了多......
目的:探讨经鼻蝶入路单纯肌肉填塞法治疗鞍内蛛网膜囊肿的临床效果。方法:回顾性分析2014年1月至2020年2月于郑州大学第一附属医院......
Molecular mechanism and therapeutic targeting of necrosis, apoptosis, pyroptosis, and autophagy in c
Cell death occurs in various tissues and organs in the body. It is a physiological or pathological process that has diff......
Chinese medicine (CM) has a good clinical effect on osteoarthritis (OA),but the mechanism is not very clear.Evidence-bas......
The Current Situation on Major Depressive Disorder in China: Research on Mechanisms and Clinical Pra
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Phytophthora sojae TatD Nuclease Positively Regulates Sporulation and Negatively Regulates Pathogene
During pathogenic interactions, both the host and pathogen are exposed to conditions that induce programmed cell death (......
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The Autophagy-related gene BcATG1 is Involved in Fungal Development and Pathogenesis in Botrytis cin
Autophagy,a ubiquitous intracellular degradation process,is conserved from yeast to human.It serves as a major survival ......
Comparison of the pathogenesis of the highly passaged MCMV Smith strain with that of the low passage
Murine cytomegalovirus(MCMV)Smith strain is widely used in mouse models to study HCMV infections.Due to highly serial pa......
Characterization of the serum metabolic profile of dairy cows with milk fever using 1 H-NMR spectros
Milk fever (MF), also known as clinical hypocalcemia, is a common calcium metabolism disorder in perinatal cows that is ......
Canine distemper virus (CDV) infects a broad range of carnivores and causes a highly contagious disease with severe immu......
Direct visualization of the novel pathogen, Spiroplasma eriocheiris, in the freshwater crayfish Spir
Spiroplasma eriocheiris is the first spiroplasma strain known to be pathogenic to freshwater crustaceans.It has caused c......
The Involvement of Protease Nexin-1 (PN-1) in the Pathogenesis of Intervertebral Disc (IVD) Degenera
Objective Protease Nexin-1(PN-1)has been found to interact with both extracellular matrix(ECM)and intracellular cartilag......
The pathogenesis of pseudarthrosis in ankylosing spondylitis:inflammatory or traumatic?a retrospecti
Study Design Retrospective case series Purpose To investigate the pathogenesis of pseudarthrosis(Andersson lesion)in ank......
Cervicalvertigoischaracterizedbyvertigofromcervicalspine.However,whethercervicalvertigoisan independententitystillremain......
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Relationship analysis between human ABO blood group and pancreatic ductal adenocarcinoma and literat
Objective Objective: To analysis the relationship between ABO blood group and pancreatic ductal adenocarcinoma.In the pa......
Purpose Adolescent idiopathic scoliosis(AIS),the most common pediatric spinal deformity,is considered a complex genetic ......
Acute pancreatitis (AP) is a complex disease which results in significant morbidity and mortality.For many decades it ha......
RolesofTGF-β/Smadsignalingpathwayinpathogenesisand developmentofglutealmusclecontracture
PURPOSE OF THE STUDY: Glutealmusclecontracture(GMC)isachronicfibroticdiseaseofglutealmuscleswhichischaracterizedbyexcess......
Malignant peripheral nerve sheath tumor(MPNST)is a rare and aggressive soft tissue sarcoma for which effective treatment......
Paroxysmal kinesigenic dyskinesia(PKD)is an autosomal dominant movement disorder with characteristics of involuntary att......
The Prevalence,Certain Pathogenesis,Diagnosis and Intervention about Age Associated Memory Impairmen
Objects:To study the prevalence,pathogenesis and intervention about mild cognitive impairment in the old -old.Method A s......
The Prevalence,Certain Pathogenesis and Preliminary Intervention about Mild Cognitive Impairment (MC
Objects:To study the prevalence,pathogenesis and intervention about mild cognitive impairment in the old-old.Method:A sa......
Amyloid-beta(Aβ)plays a pivotal role in the pathogenesis of Alzheimers disease(AD).The physiological capacity of periph......
Indicative prognosis by diffusion tensor imaging and magnetic resonance spectroscopyin Marchiafava-B
Purpose Marchiafava-Bignami disease(MBD)is characteristic of primary degenerative disorder of the corpus callosum(CC),wh......
Stevens-Johnson syndrome and toxic epidermal necrolysis in a 6-year-old child:a case report and an u
Introduction: Stevens-Johnson syndrome(SJS)and toxic epidermal necrolysis(TEN)in children are rare,but potentially life-......
RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, can
There are remarkable disparities among patients of different races with prostate cancer;however, the mechanism underlyin......
Kidney tissue targeted metabolic profiling of renal interstitial fibrosis rats induced by unilateral
Aim Renal interstitial fibrosis (RIF) is a common final pathological process in the progression of kidney disease.To inv......
