GLUTAMATE相关论文
Parkinson\'s disease (PD) is the second most common and fastest-growing neurodegenerative disorder.In recent years,it ......
Excess extracellular glutamate leads to excitotoxicity, which induces neuronal death through the overactivation of N-met......
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TNP-ATP is Beneficial for Treatment of Neonatal Hypoxia-Induced Hypomyelination and Cognitive Declin
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N-acetylaspartylglutamate Inhibits Heroin Self-Administration and Heroin-Seeking Behaviors Induced b
Activation of presynaptic group Ⅱ metabotropic glutamate receptors (mGluR2/3) inhibits drug reward and drug-seeking beh......
L-DOPA therapy,as the gold standard in PD,is accepted to relieve motor symptoms in early Parkinsons disease,whereas the ......
Real-time measuring of glutamate flux and electrophysiological signal with nano-modified microelectr
The central nervous system(CNS)mainly relies on neurotransmitter release and electrophysiological signal to complete the......
An enzyme-based MEA probe for second-by-second measurements of L-glutamate release and uptake in rat
L-glutamate(Glu)neurotransmitter plays a predominant role in the mammalian central nervous system,associated with normal......
Optimization of Organic Nitrogen Sources for the L-glutamate Production by Corynebacterium glutamicu
In glutamate fermentation, optimizations of production medium and fermentation parameters have been the mainly strategy ......
Regulation of Taste Active Components in Meat by Dietary Valine-Metabolome Analysis related on Val a
In recent years,functionality and palatability are needed for foods.Improvement of meat quality has been studied in the ......
Osteoarthritis(OA)is a commom form of arthritis in humans.It has long been regarded as a non-inflammatory disease,but ad......
The functions of thalamus are the relaying of sensory and motor signals to the cortex, and the regulation of consciousne......
Cultured astrocytes from Wistar rats are more susceptible to swelling induced by glutamate than thos
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Glutamate(Glu),the most important excitatory neurotransmitter in the central nervous system(CNS),mediates synaptic plast......
Etidronate and trisphosphonates are new potential candidates for neuroprotective drugs for Alzheimer
Objective Bisphosphonates(BP)is a category of drugs that are used to treat various bone diseases,such as osteoporosis,Pa......
Aquaporin 1 specifically accumulate around astrocyte nuclear to mediates Glu-induced nuclear swellin
Objective Aquaporins (AQPs) belong to the water-specific channel protein family and have been reported to involve in cel......
study on the dynamic expression of the excitatory inhibitory balance in the retina of guinea pigs of
Objective Gamma-aminobutyric acid(GABA)and glutamate are major inhibitory and excitatory neurotransmitter within the ret......
Bax-related autophagy as a relevant mechanism in bleomycin-induced lung fibrosis via peripheral glut
Glutamate is an important excitatory neurotransmitter in the CNS.Extracellular glutamate can be regulated by excitatory ......
Objective: Recently,we have demonstrated that glutamate,the most abundant excitatory neurotransmitter in the central ner......
The red nucleus glutamate plays a facilitated role in the development of SNI-induced neuropathic all
Objective Glutamate(Glu)is an excitatory neurotransmitter in the central nervous system and plays an important role in t......
The role of group Ⅱ metabotropic glutamate receptors in the striatum in electro-acupuncture treatmen
Aims: Glutamatergic transmission may play a critical role in the pathogenesis of Parkinsons disease(PD).Electroacupunctu......
Neurotensinergic augmentation of glutamate release at the perforant path-granule cell synapse in rat
Neurotensin(NT)serves as a neuromodulator in the brain where it is involved in modulating a variety of physiological fun......
Objective This study was undertaken to determine the role of glial glutamate transporter (GLT)-1 a, one of splice varian......
Introduction Glutamate is a well-defined excitatory neurotransmitter in the central nervous system and contributes to ne......
Sedative and hypnotic effects of NHBA and its relationship with amino acid neurotransmitters in mous
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Glutamate stimulation induces a two-phase cofilin rod formation mediated by both NMDA and non-NMDA r
Objective Cofilin is the major actin-depolymerizing factor in the CNS for regulation of actin dynamics.Neurodegenerative......
Oxytocin receptor involved in the inhibition of oxytocin on methamphetamine-induced glutamate releas
Objective Recent studies showed that the oxytocin (OT),a neurohypophyseal neuropeptide which affected adaptive central n......
Objective Gamma-aminobutyric acid(GABA)and glutamate are major inhibitory and excitatory neurotransmitter within the ret......
DREAM is expressed in primary culture of astrocyte and can be regulated by substance P, bradykinin a
DREAM (downstream regulatory element antagonist modulator),was involve in pain modulation.Its roles in astrocyte remains......
Glutamate uptake triggers astrocytic nuclear swelling through aquaporin-1 located on nuclear membran
In the central nervous system,excitatory neurotransmitter glutamate is mainly released from neuron and uptaken by astroc......
We recently found astrocytes in primary culture expressed hyperpolarization-activated cyclic nucleotide-gated (HCN) gene......
Glycine binding sites of presynaptic NR2B-containing NMDA autoreceptors may tonically regulate gluta
Johnson and Ascher first demonstrated that,in the vertebrate central nervous system (CNS),exogenously applied glycine po......
Better calcium homeostasis was maintained in cortical neurons of ground squirrels than rats in prolo
Excitotoxicity is one of the leading causes inducing neuronal death.Here, we reported that cultured cortical neurons fro......
Inhibition of corticorstriatal glutamatergic transmission mediated the behavioral improvement of ele
The major feather of Parkinsons disease (PD) is the loss of dopaminergic (DA) neurons in substantia nigra pars compacta ......
The aim of this study is to investigate the response of astrocytes (AS) in rat supraoptic nucleus (SON) to different osm......
Quantitative measurement of glutamate uptake by isocratic reversed high performance liquid chromatog
In the central nervous system,neuronal-released glutamate is mainly uptaken by astrocyte.However,the fate of uptaken glu......
Cell swelling is one of the early cellular responses to injury.In many pathological conditions (e.g.ischemia,epilepsy,br......
Increased Na+/Ca2+ exchanger activity promotes resistance to excitotoxicity in cortical neurons of t
Ground squirrel,a hibernating mammalian species,is more resistant to ischemic brain stress than rat.Gaining insight into......
It is evidenced that inflammation is involved in the pathogenesis of anxiety disorder,as well as the dysfunction of glut......
EFFECTS OF ENDOGENOUS MELATONIN ON GLUTAMATE AND GABA RHYTHMS IN THE STRIATUM OF UNILATERAL 6-HYDROX
We have previously reported a time-dependent increase in melatonin (MLT) and decrease In dopamine (DA) in striatal dialy......
1.Intrathecal injection of bupivacaine on the contents of excitatory and inhibitory amino acids of s
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The electroconvulsive shock of different electric quantity and of different treatment number aggrava
Objective This study explore the effect of the electroconvulsive shock of different electric current and different durat......
Comparison of the neuropsychology mechanisms of 2,6-Diisopropylphenol and NMDA receptor antagonist p
Objective This study explore the reversion of 2,6-Diisopropylphenol and NMDA receptor antagonist against the impairment ......
N-acetylaspartylglutamate (NAAG) peptidase inhibitor 2-PMPA elevates extracellular NAAG levels and i
Phencyclidine (PCP), an open channel antagonist of the NMDA subtype of glutamate receptor, induces schizophrenia-like be......
The effects of ANEPⅢ, a new recombinant neurotoxic peptide, on behavior and brain neuronal activity in animal studies h......
Effects of Ginsenoside Rgl on Acetylcholine,Choline,Glutamate and Taurine in Medial Prefrontal Corte
Objective: To study the role of Ginsenoside Rgl on improving cognitive impairment of neurodegenerative diseases,dual-pro......
Taurine protecting ganglion cells against glutamate-induced ezcitotozicity by stabilizing calcium ho
Taurine is known to act as an osmoregulator and an inhibitory neuromodulator in central nervous system．Recent researches ......
Effect of KA and NMDA lesion of the medial prefrontal cortex and dorsal hippocampus on the methamphe
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Glutamate (Glu) is a major excitatory neurotransmitter in central nervous system, but high extracellular concentration o......
