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[会议论文] 作者：Yang Luan,Guozhen Xing,Jin Ren,
来源：3rd Asian Conference on Environmental Mutagens & 15th Confer 年份：2012
Hepatic CYPs involved in both the detoxification and metabolic activation of many carcinogens.In order to reveal the role of hepatic cytochrome P450 in hepatic versus extra-hepatic metabolism of carci...
[会议论文] 作者：Tiangang Ma,Jin Ren,Jinzhi Yin,Zhongsen Ma,
来源：2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议 年份：2014
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[会议论文] 作者：Ying Xiao,Jin Ren,Jun Gu,Hongli Zhu,
来源：第67届世界药学大会(67th International Conference of FIP) 年份：2007
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Validation and application of a generic method for the determination of a humanized monoclonal antib
[会议论文] 作者：Guozhen Xing,Xiaoli Liu,Qiuping Qin,Jin Ren,
来源：第四届药物毒理学年会 年份：2014
Background Because of physiological and genetic similarities to humans,cynomolgus monkeys have been frequently used in preclinical studies for humanized antibody drugs.A generic method for the detecti...
[会议论文] 作者：Ying Xiao,Jun Gu,Hongli Zhu,Jin Ren,
来源：第67届世界药学大会(67th International Conference of FIP) 年份：2007
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Approaches to prevent the patients with chronic airway diseases from exacerbation in the haze weathe
[会议论文] 作者：Jin Ren,Jing Liu,Zhongsen Ma,Bo Li,Dan Yu,
来源：2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议 年份：2014
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Approaches to prevent the patients with chronic airway diseases from exacerbation in the haze weathe
[会议论文] 作者：Jin Ren,Bo Li,Dan Yu,Jing Liu,Zhongsen Ma,
来源：2014中华医学会呼吸病学年会暨第十五次全国呼吸病学学术会议 年份：2014
Haze weather is becoming one of the biggest problems in many big cities in China.It triggers both public anxiety and official concerns.Particulate matter (PM) plays the most important role in causing...
Development and validation of an enzymE-linked immunosobent assay for the determination of a humaniz
[会议论文] 作者：Qiuping Qin,Jinli Gao,Wenjing Fang,Xiaoqiu Wang,Likun Gong,Jin Ren,
来源：第四届药物毒理学年会 年份：2014
Background Biosimilars are biologic medical products and receiving increasing attention in the pharmaceutical field.Cynomolgus monkeys are used in preclinical studies for biosimilars due to physiologi...
Development and validation of a screening enzyme-linked immunosobent assay for the detection of anti
[会议论文] 作者：Qiuping Qin,Wenjing Fang,Jinli Gao,Xiaoqiu Wang,Likun Gong,Jin Ren,
来源：第四届药物毒理学年会 年份：2014
Background Biosimilars are large molecules that have a greater potential to elicit anti-drug antibody(ADA)response,in preclinical studies,ADA can affect drug exposure,causing problems in the interpret...
[会议论文] 作者：Hongxia Liu,Shuqin Wu,Jingmou Yu,Dun Fan,Jin Ren,Lei Zhang,Jianguo Zhao,
来源：2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 年份：2016
Reduction-sensitive chondroitin sulfate A(CSA)-based micelles were developed.CSA was conjugated with deoxycholic acid(DOCA)via a disulfide linkage....
[会议论文] 作者：Mengjun Wu,Chenchen Feng,Mingxia Liu,Guozhen Xing,Xinming Qi,Likun Gong,Yang Luan,Jin Ren,
来源：3rd Asian Conference on Environmental Mutagens & 15th Co 年份：2012
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A validation safety pharmacology study of the central nervous system, employing a functional observa
[会议论文] 作者：Li-ping HU,Wei-jun ZHENG,Long-sheng ZHANG,Xiao-qiang CHEN,Liang-shun LI,Ming LI,Hong YU,Jin REN,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
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Evaluation of human monoclonal antibody toxicity, toxicokinetics and immunogenicity in cynomolgus mo
[会议论文] 作者：Hong YU,Wei-jun ZHENG,Qiu-ping QIN,Jun-wen QIAO,Jin REN,Patricia RYAN,Meina LIANG,Dale THUR-MAN,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
...
[会议论文] 作者：Mengjun Wu,Guozhen Xing,Xinming Qi,Chenchen Feng,Mingxia Liu,Likun Gong,Yang Luan,Jin Ren,
来源：3rd Asian Conference on Environmental Mutagens & 15th Confer 年份：2012
...
A validation safety pharmacology study of the central nervous system, employing a functional observa
[会议论文] 作者：Li-ping HU,Wei-jun ZHENG,Long-sheng ZHANG,Xiao-qiang CHEN,Liang-shun LI,Ming LI,Hong YU,Jin REN,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: The objective of this study was to establish and validate a functional observational battery (FOB) at the Center for Drug Safety Evaluation & Research (CDSER) that provides a basic neurological a...
Evaluation of human monoclonal antibody toxicity, toxicokinetics and immunogenicity in cynomolgus mo
[会议论文] 作者：Hong YU,Patricia RYAN,Meina LIANG,Wei-jun ZHENG,Qiu-ping QIN,Dale THUR-MAN,Jun-wen QIAO,Jin REN,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: A human monoclonal antibody was administered intravenously for 4-week in cynomolgus monkeys.The aim of this study was to characterize the toxicity of the antibody and in particular, the exposure-...
Moxifloxacin: cardiovascular effects in conscious, Jacketed cynomolgus monkeys following oral (Nasog
[会议论文] 作者：Miao-miao HU,Guo-zhen XING,Matthew SKINNER,Hong YU,Shao-dong WANG,Li ZHAO,Wei-jun ZHENG,Jin REN,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: Moxifloxacin is a fluoroquinolone with a broad spectrum of antibacterial activity.The aim of this study was to investigate the cardiovascular effects of moxifloxacin, administered to conscious, j...
Silica nanopaticles induce male reproductive toxicity by inhibiting the start and process of meiosis
[会议论文] 作者：Zbang Jin,Ren Lihua,Zou Yang,Zhang Lianshuang,Wei Jialiu,Li Yanbo,Wang Ji,Sun Zhiwei,Zhou Xianqing,
来源：第6届全国动物生理生态学学术研讨会 年份：2016
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[会议论文] 作者：,Yumei Cheng,Deheng Wang,Chunpu Li,Ming Du,Jianhua Sun,Qiuping Qin,Hong Liu,Meiyu Geng,Likun Gong,Jin Ren,
来源：第二届(2016年)中国安全药理学学术年会暨第五届安全药理学国际学术研讨会 年份：2016
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Detection of QTc interval prolongation using Jacketed External Telemetry in cynomolgus monkeys: infl
[会议论文] 作者：Guozhen Xing,Miaomiao Hu,Matthew Skinner,Hong Yu,Shaodong Wang,Li Zhao,Weijun Zheng,Likong Gong,Ming Li,Jin Ren,
来源：第四届药物毒理学年会 年份：2014
Introduction Assessment of the electrocardiogram(ECG)within toxicology studies has traditionally been performed using methods that require either physical or chemical restraint and which only provide...
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