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[期刊论文] 作者：Jia-jia Shang,Chang-yu Wang,Ming-zhi Shen,Shuai Jiang,Tian Li,Wen-cheng Di,Ying Chen,He Li,Ye-dong Cheng,
来源：中国药理学报（英文版） 年份：2022
High mobility group box 1(HMGB1)is a ubiquitous nuclear protein that is present in almost all cells and regulates the activity of innate immune responses in both intracellular and extracellular settings.Current evidence suggests that HMGB1 ......
N-n-Butyl haloperidol iodide ameliorates liver fibrosis and hepatic stellate cell activation in mice
[期刊论文] 作者：Dai-fei Shen,He Cheng,Bo-zhi Cai,Wen-feng Cai,Bin Wang,Qing Zhu,Yue-bin Wu,Man Liu,Run-ji Chen,Fen-fei,
来源：中国药理学报（英文版） 年份：2022
N-n-Butyl haloperidol iodide(F2)is a novel compound that has antiproliferative and antifibrogenic activities.In this study we investigated the therapeutic potential of F2 against liver fibrosis in mice and the underlying mechanisms.Two wide......
[期刊论文] 作者：Qingfeng Jiang,Bowen Meng,Zheng Wang,Peng Qian,Jianan Zheng,Jiawei Jiang,Cheng Zhao,Juzhi Hou,Guanghui,
来源：科学通报（英文版） 年份：2022
One of the Holocene abrupt events around 4200 years ago,lasting for ～ 200 years,is thought to have caused cultural disruptions,yet terrestrial climatic status right after the cold/dry event remains poorly defined and is often presumed that a......
[期刊论文] 作者：Zhiyuan Liu,Qiumin Le,Yanbo Lv,Xi Chen,Jian Cui,Yiming Zhou,Deqin Cheng,Chaonan Ma,Xiujuan Su,Lei Xiao,
来源：细胞研究（英文版） 年份：2022
Dopamine (DA) level inthe nucleus accumbens (NAc) is critical for reward and aversion encoding.DA released from the ventral mesencephalon (VM) DAergic neurons increases the excitability of VM-projecting D1-dopamine receptor-expressing mediu......
[期刊论文] 作者：Xiao Tiantian,Ni Qi,Chen Huiyao,Wang Huijun,Yang Lin,Wu Bingbing,Cao Yun,Cheng Guoqiang,Wang Laishuan,
来源：中华医学杂志英文版 年份：2022
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[期刊论文] 作者：Tiantian Xiao,Qi Ni,Huiyao Chen,Huijun Wang,Lin Yang,Bingbing Wu,Yun Cao,Guoqiang Cheng,Laishuan Wang,
来源： 年份：2022
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[期刊论文] 作者：Jian,Fangming Mei,Yifang Zhang,Fangfang Li,Nan Chen,Tian Li,Linying Du,Li Ding,Zhongxue Wang,Xinxiu Cheng,
来源：分子植物（英文版） 年份：2022
Drought is a major environmental factor limiting wheat production worldwide,and developing drought-tolerant cultivars is a central challenge for wheat breeders globally.Therefore,it is important to identify genetic components determining dr......
Non-fullerene acceptor pre-aggregates enable high efficiency pseudo-bulk heterojunction organic sola
[期刊论文] 作者：Donghui Li,Chuanhang Guo,Xue Zhang,Baocai Du,Cong Yu,Pang Wang,Shili Cheng,Liang Wang,Jinlong Cai,Hui,
来源：中国科学：化学（英文版） 年份：2022
Pseudo-bulk heterojunction(BHJ)fabricated by sequential casting of donor and acceptor layers has been recently demonstrated as a superior structure to prepare organic solar cells(OSCs)with enhanced efficiency compared to the conventional BH......
[期刊论文] 作者：Yuxin Wang,Hua Zhang,Huaixin Yang,Xiaoli Dong,Kun Jiang,Jiangping Hu,Bosen Wang,Jianping Sun,Jinguang Cheng,
来源：中国物理B（英文版） 年份：2022
Recently,transition-metal-based kagome metals have aroused much research interest as a novel platform to explore exotic topological quantum phenomena.Here we report on the synthesis,structure,and physical properties of a bilayer kagome latt......
[期刊论文] 作者：Lijing CHENG,John ABRAHAM,Kevin E.TRENBERTH,John FASULLO,Tim BOYER,Michael E.MANN,Jiang ZHU,Fan WANG,,
来源：大气科学进展（英文版） 年份：2022
The increased concentration of greenhouse gases in the atmosphere from human activities traps heat within the climate system and increases ocean heat content (OHC). Here, we provide the first analysis of recent OHC changes through 2021 from......
Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexinl in acute kidney dise
[期刊论文] 作者：Fan Yin,Pei-qing Zheng,Liu-qi Zhao,Yan-zhe Wang,Nai-jun Miao,Zhuan-li Zhou,Qian Cheng,Pan-pan Chen,Hong-yan,
来源：中国药理学报（英文版） 年份：2022
Ischemia/reperfusion(I/R)injury is a major cause of acute kidney injury(AKI)in clinic.The activation of NLRP3 inflammasome is associated with inflammation and renal injury in l/R-induced AKI.In the current study we explored the molecular an......
[期刊论文] 作者：J Langer,Ali Tafreshi,Luis Paz-Ares,Hans-Georg Kopp,Jeronimo Rodríguez-Cid,Dariusz M Kowalski,Ying Cheng,
来源：中国肺癌杂志 年份：2022
背景与目的此项探索性分析回顾评价了晚期非小细胞肺癌(non-small cell lung cancer,NSCLC)患者的结局,旨在确定基线时合并脑转移是否会影响一线应用帕博利珠单抗联合化疗(pembrolizumab plus chemotherapy,PC)比对单用化疗的疗效.患者和方法对KEYNOTE-021队列G......
[期刊论文] 作者：Lin Wang,Li Han,Wanlong Guo,Libo Zhang,Chenyu Yao,Zhiqingzi Chen,Yulu Chen,Cheng Guo,Kaixuan Zhang,Chia-Nung,
来源：光：科学与应用（英文版） 年份：2022
Despite the considerable effort, fast and highly sensitive photodetection is not widely available at the low-photon-energy range (～meV) of the electromagnetic spectrum, owing to the challenging light funneling into small active areas with ef......
Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomi
[期刊论文] 作者：Dongyuan Ma,Lu Wang,Jianwei Jiao,Xiangdong Fang,Cheng-Ran Xu,Longqi Liu,Xun Xu,Berthold G(o)ttgens,Cheng,
来源：细胞研究（英文版） 年份：2022
Limited knowledge of cellular and molecular mechanisms underlying hematopoietic stem cell and multipotent progenitor (HSC/MPP)expansion within their native niche has impeded the application of stem cell-based therapies for hematological mal......
[期刊论文] 作者：Cao,Fusheng Chen,Ming-Cheng Chen,Xiawei Chen,Tung-Hsun Chung,Hui Deng,Yajie Du,Daojin Fan,Ming Gong,Cheng,
来源：科学通报（英文版） 年份：2022
To ensure a long-term quantum computational advantage,the quantum hardware should be upgraded to withstand the competition of continuously improved classical algorithms and hardwares.Here,we demonstrate a superconducting quantum computing s......
Metabolic Dysfunction-associated Fatty Liver Disease is Associated with Greater Impairment of Lung F
[期刊论文] 作者：,Qiang-Qiang Shi,Teng-Fei Zhou,Yang Chen,Huai Zhang,Hui Cai,Zhi-Wei Xu,Shuan-Ying Yang,Hai Lin,Zhe Cheng,
来源：临床与转化肝病杂志（英文版） 年份：2022
Background and Aims: We compared lung function parameters in nonalcoholic fatty liver disease (NAFLD) and metabolic dysfunction-associated fatty liver disease (MAFLD), and examined the association between lung function parameters and fibros......
Parallel selection of distinct Tof5 alleles drove the adaptation of cultivated and wild soybean to h
[期刊论文] 作者：Lidong Dong,Qun Cheng,Chao Fang,Lingping Kong,Hui Yang,Zhihong Hou,Yongli Li,Haiyang Nan,Yuhang Zhang,
来源：分子植物（英文版） 年份：2022
Photoperiod responsiveness is a key factor limiting the geographic distribution of cultivated soybean and its wild ancestor.In particular,the genetic basis of the adaptation in wild soybean remains poorly understood.In this study,by combini......
[期刊论文] 作者：Cheng Wang,Mingtao Huang,Congcong Chen,Yuancheng Li,Na Qin,Zijian Ma,Jingyi Fan,Linnan Gong,Hui Zeng,,
来源：中国科学：生命科学（英文版） 年份：2022
Adenosine-to-inosine (A-to-I) RNA editing is a widespread posttranscriptional modification that has been shown to play an important role in tumorigenesis.Here,we evaluated a total of 19,316 RNA editing sites in the tissues of 80 lung adenoc......
[期刊论文] 作者：Pu,Leilei Chen,Dong Guo,Hongfei Jiang,Bo He,Siyuan Qin,Kui Wang,Na Li,Jingwei Feng,Jing Wen,Shipeng Cheng,
来源：中国科学：生命科学（英文版） 年份：2022
The changes associated with malignancy are not only in cancer cells but also in environment in which cancer cells live.Metabolic reprogramming supports tumor cells\'high demand of biogenesis for their rapid proliferation,and helps tumor cel......
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