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[会议论文] 作者：Yanan Niu,Jin-jian Lu,Xiuping Chen,
来源：第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 年份：2016
Objective: 2-Methoxy-6-acetyl-7-methyljuglone(MAM)is an active naphthoquinone component of Polygonum cuspidatum used as Chinese herb medicine for treatment...
Inducible and constitutive ex-pression of NOX4 determines the endothelial cell fates in re-sponse to
[会议论文] 作者：Xiuping Chen,Wenwen Zhao,Haitao Feng,
来源：第18届中国南方国际心血管病学术会议 年份：2016
Documented studies have suggested that NADPH oxidases (NOXs) NOX1,NOX2,and NOX5 promote vessel wall apoptosis,whereas the role of NOX4 remains controver-sial.In this study,we studied the role of NOX4...
Alisol B induces endoplasmic reticulum stress and activates a protective NF-κB nuclear translocation
[会议论文] 作者：Ya-Fei Liu,Xiuping Chen,Yi-Tao Wang,Jin-Jian Lu,
来源：2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会 年份：2016
Objective: Emerging evidence suggests that the natural products have the bioactivity to induce cancer cells apoptotic death and have the potential therapeutic effects on colorectal cancer.In this stud...
Osthole inhibited epithelial-mesenchymal transition(EMT)by suppressing NF-κB mediated Snail activati
[会议论文] 作者：Xiuping Chen,Haitao Feng,Jin-Jian Lu,Yitao Wang,
来源：2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会 年份：2016
Objective: Osthole(OST),an active constituent of Chinese herb Cnidium monnieri,has been reported to inhibit cancer metastasis while the mechanisms remains unclear.Here,we studied the inhibitory effect...
[会议论文] 作者：Yanan Niu,Jin-jian Lu,Yitao Wang,Xiuping Chen,
来源：2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会 年份：2016
Objective: 2-Methoxy-6-acetyl-7-methyljuglone(MAM)is an active naphthoquinone component of Polygonum cuspidatum used as Chinese herb medicine for treatment of inflammation,hyperlipidemia and cancer.Th...
Alisol B induced endoplasmic reticulum stress and activated a protective NF-κB nuclear translocation
[会议论文] 作者：Ya-Fei Liu,Xiuping Chen,Yi-Tao Wang,Jin-Jian Lu,
来源：第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 年份：2016
Objective: Emerging evidence suggests the natural products and compounds have bioactivity to induce cancer cells apoptotic death and have the potential therapeutic effects on colorectal cancer.In this...
Toosendanin inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) through ERK pathway i
[会议论文] 作者：Weiwei Luo,Jin-Jian Lu,Xiuping Chen,Yitao Wang,
来源：中华中医药学会中药实验药理分会第十二次学术会议 年份：2016
Epithelial-mesenchymal transition(EMT),the transdifferentiation of epithelial cells into mesenchymal cells,has been reported to play an important role in the cancer cells metastasis and provides novel...
Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-κB medi
[会议论文] 作者：Haitao Feng,Jin-Jian Lu,Yitao Wang,Xiuping Chen,
来源：中华中医药学会中药实验药理分会第十二次学术会议 年份：2016
...
[会议论文] 作者：Wenshun Hu,Qizhi Xu,Fan Jiang,Xiuping Chen,Shaoquan Zheng,
来源：The Second Asian Horticultural Congress(第二届亚洲园艺大会) 年份：2016
...
Chelerythrine induced autophagy and inhibited the AKTmTOR pathway in non-small cell lung cancer A549
[会议论文] 作者：Zheng-Hai Tang,Wen-Xiang Cao,Zhao-Yu Wang,Xiuping Chen,Jin-Jian Lu,
来源：第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 年份：2016
Objective: Chelerythrine(CHE),a natural benzo[c]phenanthridine alkaloid present in a number of plant species,has been known to exert various pharmacological...
[会议论文] 作者：Jie Yu,Hongwei Gao,Jinjian Lu,Yitao Wang,Xiuping Chen,
来源：2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会 年份：2016
Objective: Doxorubicin is a widely used antineoplastic agent in clinics for treating a wide range of cancers.However,the clinical use is largely limited by its cardiotoxicity of the heart.DS-36 is a n...
Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell
[会议论文] 作者：Zheng-Hai Tang,Min-Xia Su,Wen-Xiang Cao,Xiuping Chen,Jin-Jian Lu,
来源：第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 年份：2016
Osimertinib(OSI),also known as AZD9291,is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor that has been approved for the treatment of non-small cell lung cancer(NSCLC)pat...
Protective effect of natural products against doxorubicin-induced cardiotoxicity:A systematic review
[会议论文] 作者：Jie Yu,Changxi Wang,Ying Hou,Jin-Jian Lu,Xiuping Chen,
来源：第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 年份：2016
Background: Doxorubicin(Dox),an anthracycline antibiotic,is one of the most potent and widely used chemotherapeutic agents for various types of solid tumors.Unfortunately,its clinical application is t...
[会议论文] 作者：han jibin,zou lijuan,xu xiuping,chen hui,qiu haibo,
来源：中华医学会第10次全国重症医学大会 年份：2016
Objective Catheter related bloodstream infection(CRBSI) is associated with high morbidity and mortality.Ethanol locks have been applied in several studies to reduce the incidence of CRBSI....
Dihydrotanshinone I Attenuates Atherosclerosis in ApoE-deficient Mice: Role of NOX4/NF-κB Mediated L
[会议论文] 作者：Chunxia Li,Qin Wu,Jingshan Shi,Wenwen Zhao,Hongwei Gao,Xiuping Chen,
来源：2016年全国抗炎免疫药理学术会议 年份：2016
...
Chelerythrine induces autophagy and inhibits the AKT/mTOR pathway in non-small cell lung cancer A549
[会议论文] 作者：Zheng-Hai Tang,Wen-Xiang Cao,Zhao-Yu Wang,Xiuping Chen,Yi-Tao Wang,Jin-Jian Lu,
来源：2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会 年份：2016
Objective: Chelerythrine(CHE),a natural benzo[c]phenanthridine alkaloid presents in a number of plant species,has been known to exert various pharmacological effects.The autophagy inducing effects and...
Treatment of osimertinib(AZD9291)-resistant non-small cell lung cancer HCC-827/OSIR cells by targeti
[会议论文] 作者：Zheng-Hai Tang,Min-Xia Su,Xia Guo,Xiao-Ming Jiang,Xiuping Chen,Jin-Jian Lu,
来源：2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会 年份：2016
Objective: The third generation epidermal growth factor receptor(EGFR)tyrosine kinase inhibitor(TKI)osimertinib(OSI,also known as AZD9291)has been approved for treatment of EGFR T790M positive mutatio...
Treatment of osimertinib(AZD9291)-resistant non-small cell lung cancer HCC-827/OSIR cells by targeti
[会议论文] 作者：Zheng-Hai Tang,Min-Xia Su,Xia Guo,Xiao-Ming Jiang,Xiuping Chen,Jin-Jian Lu,
来源：第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 年份：2016
Objective: The third generation epidermal growth factor receptor(EGFR)tyrosine kinase inhibitor(TKI)osimertinib(OSI,also known as AZD9291)has been approved for treatment of EGFR T790M positive mutatio...
Increase of reactive oxygen species-mediated apoptosis by celastrol in taxol-sensitive and-resistant
[会议论文] 作者：Zhao-Yu Wang,Zheng-Hai Tang,Wen-Xiang Cao,Xiuping Chen,Yi-Tao Wang,Jin-Jian Lu,
来源：第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 年份：2016
Objective: Taxol resistance is a major challenge in non-small cell lung cancer(NSCLC)treatment.In this study,the anti-cancer effect and mechanisms of celastrol(CEL),a triterpene molecule derived from...
[会议论文] 作者：Xiaxia Wu,Wen Sun,Xin Liu,Renyikun Yuan,Jin-Jian Lu,Xiuping Chen,
来源：第五届广州国际肿瘤学会议暨第一届中国抗癌协会肿瘤靶向治疗专业委员会年会 年份：2016
Background: Cryptotanshinone(CPT)is a natural compound that has been previously shown to possess antitumor effect against various cancer cell lines.In the present study,we explored the potential antit...
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