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[会议论文] 作者：Junhao Li,Yun Tang,Weihua Li,
来源：第十三届全国计算机化学学会会议 年份：2015
The cytochrome P450 2C19(CYP2C19)is one of the 57 drug metabolizing enzymes in humans and is responsible for the metabolism of~7-10%of drugs in clinical usa...
[期刊论文] 作者：Dongfeng HUANG,Limin WANG,Weihua LI,Xiaoxuan QIU,,
来源：Asian Agricultural Research 年份：2015
This paper firstly summarized the domestic and foreign research progress in the relationship between fertilization measures and soil fertility. It elaborated th...
[会议论文] 作者：Fuxing Li,Weihua Li,Yun Tang,Guixia Liu,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
The estrogen related receptor α(ERRα)as a subtype of estrogen related receptors was the first found nuclear receptors[1].It participates in the metabolism of the body and adjusts some diseases such as...
Computational analysis and prediction of miRNA-based pharmacogenomics on anti-cancer small molecules
[会议论文] 作者：Jie Li,Guixia Liu,Weihua Li,Yun Tang,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
In last decade,the “one drug,one gene,one disease” paradigm limited the development of new drugs,thus growing pharmacogenomic researches were reported to understand the overall genomic mechanism of me...
[会议论文] 作者：Jinya Cai,Guixia Liu,Weihua Li,Yun Tang,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Human aromatase,also known as CYP19A1,plays an essential role in catalyzing the conversion of androgens to estrogens,and therefore represents one of important drug targets for the treatment of breast...
[期刊论文] 作者：SUN Dongsheng,CHEN Qunce,WANG Zhongxiu,ZHAO Weihua,LI Awei,,
来源：Acta Geologica Sinica(English Edition) 年份：2015
Unconventional oil and gas resources have become more and more important for meeting our increasing energy needs,for conventional petroleum resources are becomi...
[会议论文] 作者：Jie Li,Yingchun Cai,Guixia Liu,Weihua Li,Yun Tang,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
In silico prediction of drug absorption,distribution,metabolism,excretion,and toxicity(ADMET)attracts great attentions in early drug discovery and design[1].Our admetSAR webserver[2] has become a usef...
Effects of receptor flexibility and active site water molecules on sites of metabolism prediction fo
[会议论文] 作者：Junhao Li,Hanwen Du,Guixia Liu,Yun Tang,Weihua Li,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Prediction of sites of metabolism(SOMs)mediated by cytochromes P450(CYPs)is of high interest in the drug discovery and development.In this work,we systematically evaluated the effects of receptor flex...
In Silico Prediction of Binding Modes between Glucagon-Like Peptide-1 Receptor and Its Endogenous Ag
[会议论文] 作者：Juan Zhang,Shikai Gu,Weihua Li,Yun Tang,Guixia Liu,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Diabetes,as a chronic metabolic disorder,has become the third major disease threatening the health of human being,and type 2 diabetes mellitus(T2DM)accounts for 90%of cases diabetes.Diabetes patients...
Application of Computational Systems Toxicology in Understanding of Drug-induced Hepatotoxicity Mech
[会议论文] 作者：Chen ZHANG,Guixia LIU,Weihua LI,Yun TANG,Philip W LEE,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Drug-induced hepatotoxicity is a leading cause of acute liver failure worldwide and one of the most frequent reasons for the withdrawal of approved drugs from the market.[1-2] Thus,drug-induced hepato...
[会议论文] 作者：Zengrui WU,Feixiong CHENG,Jie LI,Weihua LI,Guixia LIU,Yun TANG,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Computational prediction of drug-target interactions(DTIs)and drug repositioning provide low cost and high efficient ways for drug discovery.Recently,network-based approaches derived from recommendati...
Proteomic Analysis Demonstrated the Elongation of Internodes Under the Ear was Related to Hormone Ba
[会议论文] 作者：Fangfang Zhang,Zonghua Liu,Zhihui Ma,Weihua Li,Dong Ding,Zhiyuan Fu,Jihua Tang,
来源：第一届全国玉米生物学学术研讨会 年份：2015
...
Proteomic Analysis Demonstrated the Elongation of Internodes Under the Ear was Related to Hormone Ba
[会议论文] 作者：Fangfang Zhang,Zonghua Liu,Zhihui Ma,Weihua Li,Dong Ding,Zhiyuan Fu,Jihua Tang,
来源：第一届全国玉米生物学学术研讨会 年份：2015
The length of internodes under the ear in many crop plants is related to logging resistant in the field.To understand how internode morphological distinctions are related to the proteins in maize (Zea...
Proteomic Analysis Demonstrated the Elongation of Internodes Under the Ear was Related to Hormone Ba
[会议论文] 作者：Fangfang Zhang,Zonghua Liu,Zhihui Ma,Weihua Li,Dong Ding,Zhiyuan Fu,Jihua Tang,
来源：第一届全国玉米生物学学术研讨会 年份：2015
The length of internodes under the ear in many crop plants is related to logging resistant in the field.To understand how internode morphological distinctions are related to the proteins in maize (Zea...
[会议论文] 作者：Shihui Ding,Guoping Hu,Lei Chen,Guanglin Kuang,Wen Xiao,Weihua Li,Guixia Liu,Yun Tang,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
Virtual screening(VS)has become a significant tool in the drug discovery process.In this process,structure-based docking method that considering structure flexibility has attracted researchers attenti...
[会议论文] 作者：Xiaofeng Zhao,Yadong Xue,Weihua Li,Zhiyuan Fu,Haochuan Li,Jihua Tang,Dong Ding,Peng Zhao,Fangfang Zhang,
来源：第一届全国玉米生物学学术研讨会 年份：2015
...
[会议论文] 作者：Dong Ding,Peng Zhao,Fangfang Zhang,Xiaofeng Zhao,Yadong Xue,Weihua Li,Zhiyuan Fu,Haochuan Li,Jihua Tang,
来源：第一届全国玉米生物学学术研讨会 年份：2015
Heterosis has been used widely in the breeding of maize and other crops,and plays an important role in increasing yield,improving quality and enhancing stress resistance,but its molecular mechanism is...
[会议论文] 作者：Zhongjun Fu,Weihua Li,Xiaolong Xing,Mengmeng Xu,Xiaoyang Liu,Haochuan Li,Yadong Xue,Zonghua Liu,Jihua,
来源：第一届全国玉米生物学学术研讨会 年份：2015
Arsenic (As) is a toxic heavy metal that can accumulate in crops,posing a health threat to humans.The genetic mechanism of As accumulation is unclear.Here,quantitative trait locus (QTL) mapping was us...
[会议论文] 作者：Zhongjun Fu,Weihua Li,Xiaolong Xing,Mengmeng Xu,Xiaoyang Liu,Haochuan Li,Yadong Xue,Zonghua Liu,Jihua,
来源：第一届全国玉米生物学学术研讨会 年份：2015
Arsenic (As) is a toxic heavy metal that can accumulate in crops,posing a health threat to humans.The genetic mechanism of As accumulation is unclear.Here,quantitative trait locus (QTL) mapping was us...
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