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Upregulation of wild-type p53 by small molecule-induced elevation of NQO1 in non-small cell lung can
[期刊论文] 作者:Hong Yu,Hong-ying Gao,Hua Guo,Gui-zhen Wang,Yi-qing Yang,Qian Hu,Li-jun Liang,Qun Zhao,Da-wei Xie,Yu,
来源:中国药理学报(英文版) 年份:2022
The tumor suppressor p53 is usually inactivated by somatic mutations in malignant neoplasms,and its reactivation represents an attractive therapeutic strategy for cancers.Here,we reported that a new quinolone compound RYL-687 significantly ......
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