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Comparison of dimension reduction-based logistic regression models for case-control genome-wide asso
[期刊论文] 作者：Honggang Yi,Hongmei Wo,Yang Zhao,Ruyang Zhang,Junchen Dai,Guangfu Jin,Hongxia Ma,Tangchun Wu,Zhibin Hu,
来源：The Journal of Biomedical Research 年份：2015
With recent advances in biotechnology, genome-wide association study(GWAS) has been widely used to identify genetic variants that underlie human complex disease...
[期刊论文] 作者：Songyu Cao,Cheng Wang,Xinen Huang,Juncheng Dai,Lingmin Hu,Yao Liu,Jiaping Chen,Hongxia Ma,Guangfu Jin,Zhibin Hu,
来源：The Journal of Biomedical Research 年份：2013
Apoptosis plays a key role in inhibiting tumor growth, progression and resistance to anti-tumor therapy. We hypothesized that genetic variants in apoptotic gene...
Major spliceosome defects cause male infertility and are associated with non-obstructive azoospermia
[会议论文] 作者：Hao Wu,Liwei Sun,Yang Wen,Jun Yu,Feiyu Mao,Yujuan Liu,Chao Tong,Xuejiang Guo,Zhibin Hu,Jiahao Sha,Mingxi,
来源：第三届全国发育生物学大会 年份：2016
Processing of pre-mRNA into mRNA is an important regulatory mechanism in eukaryotes that is mediated by the spliceosome,a huge and dynamic ribonucleoprotein...
[期刊论文] 作者：,Yun Qian,Feng Lu,Meihua Dong,Yudi Lin,Huizhang Li,Chong Shen,Juncheng Dai,Yue Jiang,Guangfu Jin,Zhibin Hu,
来源：The Journal of Biomedical Research 年份：2014
Plasma lipid abnormalities are implicated in the pathogenic process of type 2 diabetes.The IDE-KIF11-HHEX gene cluster on chromosome 10q23.33 has been identifie...
[期刊论文] 作者：Pan,Chongqi Sun,Mingde Huang,Yao Liu,Fuzhen Qi,Li Liu,Juan Wen,Jibin Liu,Kaipeng Xie,Hongxia Ma,Zhibin Hu,
来源：The Journal of Biomedical Research 年份：2004
Certain pseudogenes may regulate their protein-coding cousins by competing for miRNAs and play an active biological role in cancer.However,few studies have focu...
SARS-CoV-2 encoded microRNAs are involved in the process of virus infection and host immune response
[期刊论文] 作者：Liu,Jianwei Wang,Yiyue Ge,Yuyu Xu,Mengchen Guo,Kai Mi,Rui Xu,Yang Pei,Qiankun Zhang,Xiaoting Luan,Zhibin Hu,
来源：生物医学研究杂志:英文版 年份：2021
The outbreak of COVID-19 caused by SARS-CoV-2 is spreading worldwide,with the pathogenesis mostly unclear.Both virus and host-derived microRNA(miRNA)play essent...
[会议论文] 作者：Dong Hang,Xiaosheng He,Ane S(o)rlie Kv(ae)rner,Andrew T.Chan,Kana Wu,Shuji Ogino,Zhibin Hu,Hongbing Shen,
来源：2019中国肿瘤学大会 年份：2019
Objective Hyperinsulinemia,high insulin-like growth factor(IGF)-1 levels,and low IGF binding protein(IGFBP)-1 levels have been implicated in the relationship of obesity and sedentary behavior with inc...
[会议论文] 作者：Lijuan Wang,Meng Zhu,Yuzhuo Wang,Jingyi Fan,Qi Sun,Xikang Fan,Junxing Xie,Juncheng Dai,Guangfu Jin,Zhibin Hu,
来源：2019中国肿瘤学大会 年份：2019
Objective Genome-wide association studies(GWASs)have identified hundreds of cancer-associated single nucleotide polymorphisms(SNPs),several of which have shown pleiotropic effects across cancers.There...
[期刊论文] 作者：Jing Wu,Yan Li,Cheng Wang,Yiqiang Cui,Tianyi Xu,Chang Wang,Xiao Wang,Jiahao Sha,Bin Jiang,Kai Wang,Zhibin Hu,
来源：基因组蛋白质组与生物信息学报（英文版） 年份：2019
Circular RNAs (circRNAs), covalently closed continuous RNA loops, are generated from cognate linear RNAs through back splicing events, and altative splicing eve...
Genetic and Molecular Characterization of H9N2 Avian Influenza Viruses Isolated from Live Poultry Ma
[期刊论文] 作者：Zhibin Hu,Fuhu Peng,Zhenghui Xiong,Wanpo Zhang,Tingting Li,Yuejun Shi,Jun Xie,Xin Jin,Jingjing Huang,,
来源：中国病毒学 年份：2021
H9N2 subtype avian influenza virus (AIV) is an influenza A virus that is widely spread throughout Asia,where it jeopardizes the poultry industry and provides genetic material for emerging human pathogens.To better understand the epidemicity......
SARS-CoV-2 encoded microRNAs are involved in the process of virus infection and host immune response
[期刊论文] 作者：Liu,Jianwei Wang,Yiyue Ge,Yuyu Xu,Mengchen Guo,Kai Mi,Rui Xu,Yang Pei,Qiankun Zhang,Xiaoting Luan,Zhibin Hu,
来源：生物医学研究杂志（英文版） 年份：2021
The outbreak of COVID-19 caused by SARS-CoV-2 is spreading worldwide,with the pathogenesis mostly unclear.Both virus and host-derived microRNA(miRNA)play essential roles in the pathology of virus infection.This study aims to uncover the mec......
The cancer-testis gene, MEIOB, sensitizes triple-negative breast cancer to PARP1 inhibitors by induc
[期刊论文] 作者：Jianshui Yang,Wenwen Yuan,Yanhui Zhu,Yan Zhou,Na Qin,Hongbing Shen,Hongxia Ma,Hongxia Wang,Xiaoan Liu,Zhibin Hu,
来源：癌症生物学与医学（英文版） 年份：2021
Objective: The newly defined cancer-testis (CT) gene, MEIOB, was previously found to play key roles in DNA double-strand break (DSB) repair. In this study, we a...
Quantitative analysis of plasma TSGs hypermethylation for the prediction of chemosensitivity in adva
[会议论文] 作者：Shiyang Pan,Erfu Xie,Fang Wang,Peijun Huang,Yan Geng,Lixia Zhang,Jian Xu,Wenying Xia,Yongqian Shu,Zhibin Hu,
来源：中华医学会第七次全国中青年检验医学学术会议 年份：2012
...
Quantitative analysis of plasma TSGs hypermethylation for the prediction of chemosensitivity in adva
[会议论文] 作者：Hong Wang,Ruihong Sun,Xuejun Qin,Yongqian Shu,Zhibin Hu,Hongbing Shen,Shiyang Pan,Erfu Xie,Fang Wang,,
来源：中华医学会第七次全国中青年检验医学学术会议 年份：2012
...
[会议论文] 作者：Yujiao Liu,Lina Wang,Haichao Zhao,Yongliang Shang,Yang Wen,Yuan Lin,Tao Zhou,Zuomin Zhou,Dong Wen,Zhibin Hu,
来源：2015第八届中国模式真菌研讨会 年份：2015
...
[期刊论文] 作者：Zijian Ma,Jingyi Fan,Linnan Gong,Hui Zeng,Liu Yang,Xianfeng Xu,Jun Zhou,Juncheng Dai,Guangfu Jin,Zhibin Hu,
来源：中国科学：生命科学（英文版） 年份：2022
Adenosine-to-inosine (A-to-I) RNA editing is a widespread posttranscriptional modification that has been shown to play an important role in tumorigenesis.Here,we evaluated a total of 19,316 RNA editing sites in the tissues of 80 lung adenoc......
Cumulative live birth rates of in vitro fertilization/intracytoplasmic sperm injection after multipl
[期刊论文] 作者：Xiumei Han,Kun Zhou,Bo Xu,Xiaoyu Liu,Hongxia Ma,Yankai Xia,Guangfu Jin,Hongbing Shen,Xiufeng Ling,Zhibin Hu,
来源：生物医学研究杂志（英文版） 年份：2020
There were few studies of cumulative live birth rates (CLBRs) based on multicenter reproductive clinical data from the general Chinese population.Here we report...
[会议论文] 作者：姜丽岩,Jiaqi Huang,Brandon W.Higgs,Zhibin Hu,Zhan Xiao,Xin Yao,Sarah Conley,Haihong Zhong,Zheng Liu,Philip,
来源：第十八届全国临床肿瘤学大会暨2015年CSCO学术年会 年份：2015
目的：小细胞肺癌是预后较差的侵袭性肿瘤。大规模的测序研究已经揭示在各种恶性肿瘤中潜在的疾病驱动基因，但目前仍有许多未知驱动基因，特别是在亚洲患者。我们开展这项基因组蓝图研究，通过探索中国小细胞肺癌患者的综合遗传蓝图与详细的临床病史，试图找到DNA修复途......
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