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[期刊论文] 作者:Wenhui Tao,Zhonggui He, 来源:亚洲药物制剂科学(英文) 年份:2018
In the field of biomedicine, stimuli-responsive drug delivery systems(DDSs) have become increasingly popular due to their site-specific release ability in respo...
[期刊论文] 作者:Longfa Kou,Zhonggui He,Jin Sun, 来源:亚洲药物制剂科学(英文) 年份:2020
To date,over 400 membrane transporters have been identified and characterized in human cells at both the molecular level and functional level.These transporters...
[会议论文] 作者:Jin Sun,Jinling Wang,Zhonggui He, 来源:2012年中国药物制剂大会——中国药学会药剂专业委员会年会、亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 年份:2012
[会议论文] 作者:Cong Luo,Jin Sun,Zhonggui He, 来源:2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 年份:2016
[会议论文] 作者:Jie Li,Jin Sun,Haiyan Li,Zhonggui He, 来源:首届亚洲药物制剂科学研讨会(1st Asian Pharmaceutical Science and Technolog 年份:2007
Purpose: To obtain relationship between retention behaviors of solutes on immobilized artificial membrane (IAM) and their absorption and distribution character in vivo.Methods: Retention factors of st...
[会议论文] 作者:He Lian,Jin Sun,Zhonggui He,Yan Liu, 来源:2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 年份:2016
[期刊论文] 作者:Xinyu Lou,Zhichao Chen,Zhonggui He,Mengchi Sun,Jin Sun, 来源:纳微快报(英文) 年份:2021
The use of bacteria to specifically migrate to cancerous tissue and elicit an antitumor immune response provides a promising platform against cancer with signif...
[期刊论文] 作者:Hong Sun,Suyan Liu,Xun Gao,Zhili Xiong,Zhonggui He,Longshan Zhao, 来源:药物分析学报(英文) 年份:2019
Drug stability is closely related to drug safety and needs to be considered in the process of drug production, package and storage. To investigate the stability...
[会议论文] 作者:Kai Liu,Jin Sun,Yongjun Wang,Yuan He,Kun Gao,Zhonggui He, 来源:首届亚洲药物制剂科学研讨会(1st Asian Pharmaceutical Science and Technolog 年份:2007
Purpose Two types of 10-hydroxycamptothecin (10-HCPT) loaded nanostructured lipid careers (NLC-F 68 and NLC-Brij 35) intended for use as the altemative formulation of 10-HCPT for parenteral administra...
[会议论文] 作者:Jianfang Liu,Jin Sun,Yongjun Wang,Xiaohong Liu,Yinghua Sun,Huan Xu,Zhonggui He, 来源:首届亚洲药物制剂科学研讨会(1st Asian Pharmaceutical Science and Technolog 年份:2007
Purpose To characterize microemulsion liquid chromatography (MELC) systems using the solvation parameter model.Methods Four microemulsion mobile phases and two micellar systems were prepared.The logar...
[期刊论文] 作者:Xinyu Lou,Dong Zhang,Hao Ling,Zhonggui He,Jin Sun,Mengchi Sun,Dongchun Liu, 来源:药学学报(英文版) 年份:2021
A commercial albumin-bound paclitaxel nano-formulation has been considered a gold stan-dard against breast cancer.However,its application still restricted unfavorable pharmacokinetics and the immunogenicity of exogenous albumin carrier.Here......
[期刊论文] 作者:Meng Li,Liwen Zhao,Tao Zhang,Yue Shu,Zhonggui He,Yan Ma,Dan Liu,Yongjun Wang, 来源:药学学报(英文版) 年份:2019
Prodrug nanoassemblies,which can refrain from large excipients,achieve higher drug loading and control drug release,have been placed as the priority in drug del...
[期刊论文] 作者:Yixin Sun,Dongyang Zhao,Gang Wang,Yang Wang,Linlin Cao,Jin Sun,Qikun Jiang,Zhonggui He, 来源:药学学报(英文版) 年份:2020
Hypoxia,a salient feature of most solid tumors,confers invasiveness and resistance to the tumor cells.Oxygen-consumption photodynamic therapy (PDT) suffers from...
[会议论文] 作者:Mengran Guo,Qiang Fu,Chunnuan Wu,Zhibin Guo,Mo Li,Jin Sun,Zhonggui He,Li Yang, 来源:2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 年份:2015
The objective of this study was to compare the in vitro and in vivo performance of rod shaped and spherical like nanocrystals for oral administration.Lovastatin (LOV) was chosen as the model drug and...
[期刊论文] 作者:Dan Li,Yingli Wang,Chang Li,Qiu Wang,Bingjun Sun,Haotian Zhang,Zhonggui He,Jin Sun, 来源:药学学报(英文版) 年份:2021
Tumor metastasis is responsible for chemotherapeutic failure and cancer-related death.More-over,circulating tumor cell (CTC) clusters play a pivotal role in tumor metastasis.Herein,we develop cancer-specific calcium nanoregulators to suppre......
[会议论文] 作者:Qiang Fu,Yongjun Wang,Yan Ma,John K Fallon,Xinggang Yang,Zhonggui He,Dan Liu,Feng Liu, 来源:2014年中国药物制剂大会——中国药学会药剂专业委员会年会、第六届亚洲阿登制药技术研讨会暨国际控释协会中国分会年会 年份:2014
Nanocarriers delivering prodrugs are important strategies to improve the in vivo effectiveness and efficiency.For therapeutical efficacy, the prodrug must hydrolyze to its parent drug after administra...
[期刊论文] 作者:Qiu Wang,Mengchi Sun,Chang Li,Dan Li,Zimeng Yang,Qikun Jiang,Zhonggui He,Huaiwei Ding,Jin Sun, 来源:亚洲药物制剂科学(英文) 年份:2021
The therapeutic strategy that gives consideration to the combination of photodynamic therapy and chemotherapy,has emerged as a potential development of effectiv...
[期刊论文] 作者:Jiang Yu,Yingli Wang,Shuang Zhou,Jinbo Li,Jiamei Wang,Dongxu Chi,Xue Wang,Guimei Lin,Zhonggui He,Yongjun, 来源:药学学报(英文版) 年份:2020
The combination of paclitaxel (PTX) and doxorubicin (DOX) has been widely used in the clinic.However,it remains unsatisfied due to the generation of severe toxi...
[期刊论文] 作者:Lingxiao Li,Shiyi Zuo,Fudan Dong,Tian Liu,Yanlin Gao,Yinxian Yang,Xin Wang,Jin Sun,Bingjun Sun,Zhonggui He, 来源:亚洲药物制剂科学(英文) 年份:2021
Homodimeric prodrug-based self-assembled nanoparticles,with carrier-free structure and ultrahigh drug loading,is drawing more and more attentions.Homodimeric prodrugs are composed of two drug molecules and a pivotal linkage.The influence of......
[期刊论文] 作者:Shenwu Zhang,Yuequan Wang,Zhiqiang Kong,Xuanbo Zhang,Bingjun Sun,Han Yu,Qin Chen,Cong Luo,Jin Sun,Zhonggui He, 来源:药学学报(英文版) 年份:2021
Pure drug-assembled nanomedicines(PDANs)are currently under intensive investigation as promising nanoplatforms for cancer therapy.However,poor colloidal stability and less tumor-homing ability remain critical unresolved problems that impede......
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