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[期刊论文] 作者：Honglei Liu,Yanda Li,Xiaowo Wang,
来源：定量生物学（英文版） 年份：2014
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[会议论文] 作者：Chao He,Xiaowo Wang,Michael Q.Zhang,
来源：第二届全国计算生物学与生物信息学学术会议 年份：2015
Many enhancers regulate their target genes via long distance interactions.High-throughput experiments like ChIA-PET have been developed to map such interact...
OP-Synthetic: identification of optimal genetic manipulations for the overproduction of native and n
[会议论文] 作者：Honglei Liu,Yanda Li,Xiaowo Wang,
来源：第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 年份：2014
Backgroud: Constraint-based flux analysis have been widely used in metabolic engineering to predict genetic optimization strategies.These methods seek to find genetic manipulations that maximally coup...
[期刊论文] 作者：Ye Yuan,Xinying Ren,Zhen Xie,Xiaowo Wang,
来源：定量生物学（英文版） 年份：2016
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CRISPR-ERA a comprehensive designer tool for CRISPR-mediated gene editing, repression and activation
[会议论文] 作者：Honglei Liu,Zheng Wei,Antonia Dominguez,Yanda Li,Xiaowo Wang,Lei S.Qi,
来源：2015合成生物学青年学者论坛 年份：2015
The CRISPR/Cas9 system has recently been developed as a powerful and flexible technology for different purposes of targeted genome engineering, including ge...
[期刊论文] 作者：Chao He,Guipeng Li,Diekidel M.Nadhir,Yang Chen,Xiaowo Wang,Michael Q.Zhang,
来源：定量生物学（英文版） 年份：2016
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[期刊论文] 作者：Tao Hu,Lei Wei,Shuailin Li,Tianrun Cheng,Xuegong Zhang,Xiaowo Wang,
来源：基因组蛋白质组与生物信息学报（英文版） 年份：2021
Isogenic cells growing in identical environments show cell-to-cell variations because of the stochasticity in gene expression. High levels of variation or noise can disrupt robust gene expression and result in tremendous consequences for ce......
[期刊论文] 作者：Qiongye Dong,Hongqing Han,Xuehui Liu,Lei Wei,Wei Zhang,Zhen Zhao,Michael Q.Zhang,Xiaowo Wang,,
来源：Journal of Genetics and Genomics 年份：2017
Cellular senescence is an irreversible cell cycle arrest program in response to various exogenous and endogenous stimuli like telomere dysfunction and DNA damag...
[期刊论文] 作者：Lei Wei,Ye Yuan,Tao Hu,Shuailin Li,Tianrun Cheng,Jinzhi Lei,Zhen Xie,Michael Q.Zhang,Xiaowo Wang,
来源：定量生物学（英文版） 年份：2019
Background:Molecular competition brings about trade-offs of shared limited resources among the cellular components,and thus introduces a hidden layer of regulat...
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