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[会议论文] 作者：Junxiang Ma,Li Chen,Dongmei Song,Yuanyuan Zhang,Piye Niu,
来源：2016中国毒理学会神经毒理专业委员会学术年会 年份：2016
Objective: Autophagy induced by methyl tert-butyl ether (MTBE) in HT-22 cells were investigated to elucidate the mechanism of MTBE toxicity.Method: In this study, HT-22 mouse hippocampal neurons cells...
[会议论文] 作者：Junxiang Ma,Li Chen,Dongmei Song,Yuanyuan Zhang,Piye Niu,
来源：中国毒理学会第五次中青年科技论坛 年份：2016
Objective: To explore the role of Sirtuins 1(SIRT1) in oxidative stress induced by methyl tert-butyl ether (MTBE).Method: In this study,HT-22 mouse hippocampal neurons cells were used to detect the to...
Danshen Liposome on Protective Effect of Oxidative Damage Caused by Silica in Human Embryonic Lung F
[会议论文] 作者：Gengxia Yang,Wei Guo,Ai Gao,Piye Niu,LiChen,Huihui Wu,Lin Tian,
来源：3rd Asian Conference on Environmental Mutagens & 15th Co 年份：2012
...
Danshen Liposome on Protective Effect of Oxidative Damage Caused by Silica in Human Embryonic Lung F
[会议论文] 作者：Gengxia Yang,Wei Guo,Ai Gao,Piye Niu,LiChen,Huihui Wu,Lin Tian,
来源：3rd Asian Conference on Environmental Mutagens & 15th Confer 年份：2012
...
Bone morphogenetic protein-7 inhibits epithelial-mesenchymal transition induced by silica through Sm
[会议论文] 作者：Gengxia Yang,Zhonghui Zhu,Yan Wang,Ai Gao,Piye Niu,Li Chen,Lin Tian,
来源：首都医科大学公共卫生学院第五届学术年会 年份：2013
Bone morphogenetic protein-7 (BMP-7) has been shown to inhibit liver and renal fibrosis in vivo and in vitro studies.There is no study to investigate BMP-7s...
Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibro
[会议论文] 作者：Zhonghui Zhu,Gengxia Yang,Yan Wang,Jing Yang,Ai Gao,Piye Niu,Lin Tian,
来源：首都医科大学公共卫生学院第三届研究生学术论坛 年份：2014
Silicosis is one of the most prevalent occupational lung diseases worldwide.This study aimed to investigate the possible mechanism that silica affected thio...
[会议论文] 作者：Ai Gao,Jing Yang,Li Chen,Lefeng Zhang,Junxiang Ma,Piye Niu,Lin Tian,
来源：环境与健康——从科研到政策国际论坛暨中国环境科学学会环境医学与健康分会2013年会 年份：2013
Objectives To identify potential methylation biomarkers of low levels benzene exposure in occupationally exposed individuals and to elucidate mechanisms of benzene hematotoxicity....
BMP-7 attenuated silica-induced pulmonary fibrosis through modulating the balance between TGF-β/Smad
[会议论文] 作者：Di Liang,Yan Wang,Zhonghui Zhu,Guoliang An,Li Chen,Piye Niu,Lin Tian,Gengxia Yang,
来源：全国卫生毒理学术研讨会 年份：2014
Objective:To investigate the antifibrotic effect and possible mechanism of bone morphogenetic protein-7 (BMP-7) on pulmonary fibrosis in RLE-6TN cells after...
BMP-7 attenuated silica-induced pulmonary fibrosis through modulating the balance between TGF-β/Smad
[会议论文] 作者：Di Liang,Yan Wang,Zhonghui Zhu,Gengxia Yang,Guoliang An,Li Chen,Piye Niu,Lin Tian,
来源：全国卫生毒理学术研讨会 年份：2014
Objective:To investigate the antifibrotic effect and possible mechanism of bone morphogenetic protein-7 (BMP-7) on pulmonary fibrosis in RLE-6TN cells after silica treatment,and verify that prevention...
Effect of bone morphogenic protein-7on the expression of epithelial-mesenchymal transition markers i
[会议论文] 作者：Yan Wang,Gengxia Yang,Zhonghui Zhu,Di Liang,Piye Niu,Ai Gao,Li Chen,Lin Tian,
来源：首都医科大学公共卫生学院第四届研究生学术论坛 年份：2015
This study presented the effect of bone morphogenic protein-7 (BMP-7)inhibiting epithelial-mesenchymal transition (EMT) in silicosis model.In vivo, Wistar r...
MicroRNA-29b inhibits the silica-induced fibroblasts activation by decreasing the extracellular matr
[会议论文] 作者：Ximeng Lian,Xiaowei Chen,Jingping Sun,Guoliang An,Xiaoli Li,Yan Wang,Piye Niu,Zhonghui Zhu,Lin Tian,
来源：首都医科大学公共卫生学院第六届研究生学术论坛 年份：2017
Silicosis is pathologically characterized by diffuse pulmonary fibrosis and abundant deposition of extracellular matrix(ECM).ECM are mainly secreted by myof...
BMP-7 Attenuated Silica-induced Pul0monary Fibrosis through Modulation of the Balance between TGF-β/
[会议论文] 作者：Di Liang,Yan Wang,Zhonghui Zhu,Gengxia Yang,Guoliang An,Xiaoli Li,Piye Niu,Li Chen,Lin Tian,
来源：首都医科大学公共卫生学院第四届研究生学术论坛 年份：2015
Objective: To investigate the anti-fibrotic effects and possible mechanisms of bone morphogenetic protein-7 (BMP-7) on silica induced fibrosis in RLE-6TN cells, and compare the preventive treatment of...
Oxidative stress and DNA Methylation mediated the anatase titanium dioxide nanoparticles-induced the
[会议论文] 作者：Wenlin Bai,Yujiao Chen,Jing Yang,Li Chen,Lefeng Zhang,Junxiang Ma,Lin Tian,Piye Niu,Ai Gao,
来源：全国卫生毒理学术研讨会 年份：2014
Objective To observe the mechanisms of the abnormal expression of miR34a and miR133a induced by the anatase titanium dioxide nanoparticles(TNPs 25nm).Methods AHH-1 cells were treated with the anatase...
The crosstalk between oxidative stress and PARP-1 methylation involved in the anatase titanium dioxi
[会议论文] 作者：Wenlin Bai,Yujiao Chen,Jing Yang,Li Chen,Lefeng Zhang,Junxiang Ma,Lin Tian,Piye Niu,Ai Gao,
来源：全国卫生毒理学术研讨会 年份：2014
Objective To study the regulating mechanisms of the anatase titanium dioxide nanoparticles(TNPs)-induced cell toxicity.Methods A549 cells were treated with the anatase titanium dioxide nanoparticles f...
[会议论文] 作者：Caixia Guo,Yinye Xia,Piye Niu,Lizhen Jiang,Junchao Duan,Yang Yu,Xianqing Zhou,Yanbo Li,Zhiwei Sun,
来源：全国卫生毒理学术研讨会 年份：2014
Despite the widespread application of silica nanopartieles (SiNPs) in industrial,commercial,and biomedical fields,their response to human cells has not been fully elucidated.Overall,little is known ab...
Abnormal expression of heat shock protein 27 and 70 in cortex of rats with spatial learning and memo
[会议论文] 作者：Li Chen,Zhixiong Shi,Zhongxin Xiao,Wei Guo,Jie Zhang,Junxiang Ma,Ai Gao,Lin Tian,Piye Niu,
来源：环境与健康——从科研到政策国际论坛暨中国环境科学学会环境医学与健康分会2013年会 年份：2013
Objectives Manganese (Mn) is an essential nutrient but excessive exposure to Mn is neurotoxic.The mechanism of Mn neurotoxicity is unclear.The present study was conducted to investigate the effect of...
[会议论文] 作者：Junxiang Ma,Li Chen,Zhixiong Shi,Xiaobo Yang,Zhongxin Xiao,Jie Zhang,Ai Gao,Lin Tian,Piye Niu,
来源：环境与健康——从科研到政策国际论坛暨中国环境科学学会环境医学与健康分会2013年会 年份：2013
Objective Parkinsons disease (PD) is a common neurodegenerative disorder, and Mn or its compounds exposure may be an important cause of it, but its mechanism still unclear to now....
[会议论文] 作者：Yuanyuan Zhang,Junxiang Ma,Dongmei Song,Li Chen,Caixia Guo,Tian Chen,Shixuan Zhang,Jiaxin Jia,Lin Tian,Piye Niu,
来源：首都医科大学公共卫生学院第六届研究生学术论坛 年份：2017
Manganese(Mn)is an important environmental risk factor for Parkinsons disease (PD)and overexposure may result in manganism,a syndrome that closely resemble PD.Autophagy is an evolutionarily conserved...
[会议论文] 作者：Junxiang Ma,Piye Niu,Chao Gui,Li Chen,Caixia Guo,Wei Guo,Zhongxin Xiao,Jie Zhang,Ai Gao,Lin Tian,
来源：首都医科大学公共卫生学院第五届学术年会 年份：2013
Objective To explore cell viability, PI3K-p85 and PI3K-p85, PI3K mRNA expression changes caused by Manganese(Mn2+) in SH-SY5Y cells.Methods SH-SY5Y cells are divided into experimental group and contro...
[会议论文] 作者：Li Chen,Piye Niu,Yang Zhang,Junxiang Ma,Caixia Guo,Wei Guo,Zhongxin Xiao,Jie Zhang,Ai Gao,Lin Tian,
来源：首都医科大学公共卫生学院第五届学术年会 年份：2013
Objective To explore cell viability, apoptosis rate and heat shock protein 10 (Hspl0) mRNA expression changes caused by Manganese(Mn2+) in SH-SY5Y cells.Methods SH-SY5Y cells are divided into experime...
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