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[期刊论文] 作者：Meng Yuan,Zi-han Song,Mei-dan Ying,Hong Zhu,Qiao-jun He,Bo Yang,Ji Cao,
来源：中国药理学报（英文版） 年份：2020
Various lipids and lipid metabolites are bound to and modify the proteins in eukaryotic cells,which are known as’protein lipidation’.There are four major type...
[期刊论文] 作者：Bin Lu,Xiao-bing Chen,Yu-cai Hong,Hong Zhu,Qiao-jun He,Bo Yang,Mei-dan Ying,Ji Cao,
来源：中国药理学报（英文版） 年份：2019
Ferroptosis is a newly characterized iron-dependent form of nonapoptotic regulated cell death triggered by lipid reactive oxygen species (LOOH).The dysregulatio...
,Inhibition of M2-like macrophages by all-trans retinoic acid prevents cancer initiation and stemnes
[期刊论文] 作者：Xue-jing Shao,Sen-feng Xiang,Ying-qian Chen,Ning Zhang,Ji Cao,Hong Zhu,Bo Yang,Qian Zhou,Mei-dan Ying,
来源：中国药理学报（英文版） 年份：2019
Emerging evidence indicates that M2-polarized tumor-associated macrophages (TAMs) directly participate in tumor initiation,progression and metastasis.However,to...
[期刊论文] 作者：Li Jiang,Xiao-bing Chen,Qian Wu,Hai-ying Zhu,Cheng-yong Du,Mei-dan Ying,Qiao-jun He,Hong Zhu,Bo Yang,,
来源：中国药理学报：英文版 年份：2021
DJ-1 is a multifunctional protein associated with cancers and autosomal early-onset Parkinson disease. Besides the well- documented antioxidative stress activity, recent studies show that DJ-1 has deglycation enzymatic activity and anti-fer......
The C terminus of DJ-1 determines its homodimerization,MGO detoxification activity and suppression o
[期刊论文] 作者：Li Jiang,Xiao-bing Chen,Qian Wu,Hai-ying Zhu,Cheng-yong Du,Mei-dan Ying,Qiao-jun He,Hong Zhu,Bo Yang,,
来源：中国药理学报（英文版） 年份：2021
DJ-1 is a multifunctional protein associated with cancers and autosomal early-onset Parkinson disease.Besides the well-documented antioxidative stress activity,recent studies show that DJ-1 has deglycation enzymatic activity and anti-ferrop......
Bis-isatin derivatives:design,synthesis,and biological activity evaluation as potent dimeric DJ-1 in
[期刊论文] 作者：Xiao-bing Chen,Hai-ying Zhu,Kun Bao,Li Jiang,Hong Zhu,Mei-dan Ying,Qiao-jun He,Bo Yang,Rong Sheng,Ji,
来源：中国药理学报（英文版） 年份：2021
The PARK7 gene(encode DJ-1 protein)was first discovered as an oncogene and later found to be a causative gene for autosomal recessive early onset Parkinson\'s disease.DJ-1 has been proposed as a potential therapeutic anticancer target due t......
Bis-isatin derivatives: design, synthesis, and biological activity evaluation as potent dimeric DJ-1
[期刊论文] 作者：Xiao-bing Chen,Hai-ying Zhu,Kun Bao,Li Jiang,Hong Zhu,Mei-dan Ying,Qiao-jun He,Bo Yang,Rong Sheng,Ji,
来源：中国药理学报：英文版 年份：2021
The PARK7 gene (encode DJ-1 protein) was first discovered as an oncogene and later found to be a causative gene for autosomal recessive early onset Parkinson’s disease. DJ-1 has been proposed as a potential therapeutic anticancer target du......
,KLF4 functions as an oncogene in promoting cancer stem celllike characteristics in osteosarcoma cel
[期刊论文] 作者：Yan-qi Zhang,Tong Xu,Bin Lu,Liang Fang,Jian-qing Gao,Lu-shan Yu,Di-feng Zhu,Bo Yang,Qiao-jun He,Mei-dan Ying,
来源：中国药理学报（英文版） 年份：2019
Despite more effective chemotherapy combined with limb-salvage surgery for the osteosarcoma treatment,survival rates for osteosarcoma patients have stagnated ov...
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