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[会议论文] 作者:Chonghui Xu, Jielin Tang, Qi Yang, Jizheng Chen, Xinwen Chen, 来源:第十三届全国免疫学学术大会摘要汇编 年份:2019
As a member of the class IIa family of histone deacetylases, the histone deacetylase 5(HDAC5) is known to be a critical transcriptional regulator and linked to prominent human diseases, including card...
[期刊论文] 作者:Lin Cao,Jizheng Chen,Yaxin Wang,Yuting Yang,Jie Qing,Zihe Rao,Xinwen Chen,Zhiyong Lou, 来源:蛋白质与细胞 年份:2019
Hepatitis C virus (HCV) is a leading cause of liver disease worldwide.Although several HCV protease/polymerase inhibitors were recently approved by U.S.FDA,the...
[期刊论文] 作者:Yuan Zhou,Qian Wang,Qi Yang,Jielin Tang,Chonghui Xu,Dongwei Gai,Xinwen Chen,Jizheng Chen, 来源:中国病毒学 年份:2018
Histone deacetylase (HDAC) inhibitors show clinical promise for the treatment of cancers,including hepatocellular carcinoma (HCC).In this study,we investigated the effect of HDAC inhibitor treatment on hepatitis C virus (HCV)replication in ......
[期刊论文] 作者:Qi Yang,Jielin Tang,Chonghui Xu,He Zhao,Yuan Zhou,Yanyi Wang,Min Yang,Xinwen Chen,Jizheng Chen, 来源:分子细胞生物学报(英文版) 年份:2020
Protein modification by small ubiquitin-like modifier(SUMO)is an important regulatory mechanism for multiple cellular pro-cesses.Although the canonical pathway...
[期刊论文] 作者:Qi Yang,Min Guo,Yuan Zhou,Xue Hu,Yun Wang,Chunchen Wu,Min Yang,Rongjuan Pei,Xinwen Chen,Jizheng Chen, 来源:中国病毒学 年份:2019
The phosphatidylserine-specific phospholipase A1 (PLA1A) is an essential host factor in hepatitis C virus (HCV) assembly.In this study,we mapped the E2,NS2 and NS5A involved in PLA1A interaction to their lumenal domains and membranous parts......
[期刊论文] 作者:Ming Zhou,Kaitao Zhao,Yongxuan Yao,Yifei Yuan,Rongjuan Pei,Yun Wang,Jizheng Chen,Xue Hu,Yuan Zhou,Xinwen, 来源:中国病毒学 年份:2017
Feasible and effective cell models for hepatitis B virus (HBV) infection are required for investigating the complete lifecycle of this virus,including the early steps of viral entry.Resistance to dimethyl sulfoxide/polyethylene glycol (DMSO......
[会议论文] 作者:Huang Cao,Xiaoxiao Gao,Qi Yang,Min Guo,Yongxuan Yao,Wandi Zhu,Yun Wang,Chunchen Wu,Jizheng Chen,Yuan, 来源:第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会 年份:2015
[会议论文] 作者:Huang Cao,Xiaoxiao Gao,Qi Yang,Min Guo,Wandi Zhu,Yongxuan Yao,Yun Wang,Chunchen Wu,Jizheng Chen,Yuan, 来源:第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会 年份:2015
The secondary structures of hepatitis C virus (HCV) RNA and the cellular proteins that bind to them are important for modulating both translation and RNA replication.However,the sets of RNA-binding pr...
[期刊论文] 作者:,Kaitao Zhao,Yongxuan Yao,Jing Guo,Xiaoxiao Gao,Qi Yang,Min Guo,Wandi Zhu,Yun Wang,Chunchen Wu,Jizheng Chen, 来源:蛋白质与细胞 年份:2018
The secondary structures of hepatitis C virus (HCV) RNA and the cellular proteins that bind to them are important for modulating both translation and RNA replic...
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