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SAF-189s,a potent new-generation ROS1 inhibitor,is active against crizotinib-resistant ROS1 mutant-d
[期刊论文] 作者：Zong-jun Xia,Yin-chun Ji,De-qiao Sun,Xia Peng,Ying-lei Gao,Yan-fen Fang,Xing-dong Zhao,Wei-bo Wang,Jian,
来源：中国药理学报（英文版） 年份：2021
The ROS1 fusion kinase is an attractive antitumor target.Though with significant clinical efficacy,the well-known first-generation ROS1 inhibitor(ROS1 i)crizotinib inevitably developed acquired resistance due to secondary point mutations in......
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