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[期刊论文] 作者:Xiao-hong CHEN,Jin-ye BAI,Fang SHEN,Ai-ping BAI,Zong-ru GUO,Gui-fang CHENG, 来源:中国药理学报(英文版) 年份:2004
AIM: To investigate the inhibitory effect of imrecoxib, a synthetic compound of completely new structure, on cyclooxygenase 1 (COX-1) and 2 (COX-2) and its anti...
[期刊论文] 作者:Hai-yan XU,Zhi-yong XIE,Peng ZHANG,Jin SUN,Feng-ming CHU,Zong-ru GUO,Da-fang ZHONG, 来源:中国药理学报(英文版) 年份:2006
Aim: To investigate the in vitro metabolism of imrecoxib in rat liver microsomes and to identify the cytochrome P450 (CYP) forms involved in its metabolism. Met...
[期刊论文] 作者:Hai-yan XU,Peng ZHANG,Ai-shen GONG,Yu-ming SUN,Feng-ming CHU,Zong-ru GUO,Da-fang ZHONG, 来源:中国药理学报(英文版) 年份:2006
Aim:Imrecoxib is a novel and moderately selective COX-2 inhibitor.The aim of the present in vitro investigation was to study the formation of the major metaboli...
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