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Identification and Characterization of Anticancer Compounds Targeting Apoptosis and Autophagy from C
[会议论文] 作者：Dan-qing Xu,Wen-wei Fu,Yuan-zhi Lao,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
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Guttiferone K Sensitizes HeLa Cells to Nutrient Stress Induced Cell Death through JNK Activation and
[会议论文] 作者：Man Wu,Xiao-yu Wang,Yuan-zhi Lao,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
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Guttiferone K Sensitizes HeLa Cells to Nutrient Stress Induced Cell Death through JNK Activation and
[会议论文] 作者：Man Wu,Xiao-yu Wang,Yuan-zhi Lao,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
Medicinal plants are excellent sources of pharmaceutical agents.In a screen designed to identify autophagic regulators from Garcinia yunnanensis, we found that Guttiferone K (GUTK) could regulate the...
Identification and Characterization of Anticancer Compounds Targeting Apoptosis and Autophagy from C
[会议论文] 作者：Dan-qing Xu,Wen-wei Fu,Yuan-zhi Lao,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
Natural compounds from medicinal plants are important resources for drug development.Active compounds targeting apoptosis and autophagy are candidates for anti-cancer drugs.In this study, we collected...
[会议论文] 作者：Xiao-xiao Meng,Xiao-yu Wang,Zheng-xiang Xia,Yuan-zhi Lao,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
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Prenylated Xanthones from the Leaves of Garcinia cowa Induce Cell Cycle Arrest, Apoptosis, and Autop
[会议论文] 作者：Zheng-xiang Xia,Dan-qing Xu,Yuan-zhi Lao,Hong-sheng Tan,Wen-wei Fu,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
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Guttiferone K, a Compound Isolated from Garcinia yunnanensis Blocks Cell Cycle Re-entry of Quiescent
[会议论文] 作者：Zhi-chao Xi,Mu Yao,Yang Li,Yuan-zhi Lao,Qi-han Dong,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
...
[会议论文] 作者：Xiao-yu Wang,Yuan-zhi Lao,Zhi-chao Xi,Man Wu,Si-ran Zhu,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
...
Prenylated Xanthones from the Leaves of Garcinia cowa Induce Cell Cycle Arrest, Apoptosis, and Autop
[会议论文] 作者：Zheng-xiang Xia,Dan-qing Xu,Yuan-zhi Lao,Hong-sheng Tan,Wen-wei Fu,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
Cervical cancer is the third most common malignancy in women, and it remains a leading cause of cancer-related death of women.Treatment usually consists of surgery in early stages and chemotherapy and...
Guttiferone K, a Compound Isolated from Garcinia yunnanensis Blocks Cell Cycle Re-entry of Quiescent
[会议论文] 作者：Zhi-chao Xi,Mu Yao,Yang Li,Yuan-zhi Lao,Qi-han Dong,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
Prostate cancer has become the most prevalent male cancer, with cancer recurrence being the main cause of mortality.Quiescent prostate cancer cells may cause cancer recurrence via cell cycle re-entry....
Screening Active Compounds from China Native Garcinia Species Reveals Novel Compounds Targeting STAT
[会议论文] 作者：Lin-feng Xu,Yuan-zhi Lao,Yan-hui Zhao,Hong-sheng Tan,Wen-wei Fu,Ying-jia Zhang,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
...
Screening Active Compounds from China Native Garcinia Species Reveals Novel Compounds Targeting STAT
[会议论文] 作者：Lin-feng Xu,Yuan-zhi Lao,Yan-hui Zhao,Hong-sheng Tan,Wen-wei Fu,Ying-jia Zhang,Hong-xi Xu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
The JAK/STAT pathway is critical in normal hematopoiesis.JAKs associate with the intracellular tails of cytokine receptors and activate members of the signal transducer and activator of transcription...
,Garcinol inhibits esophageal cancer metastasis by suppressing the p300 and TGF-β1 signaling pathway
[期刊论文] 作者：Jing Wang,Man Wu,Dan Zheng,Hong Zhang,Yue Lv,Li Zhang,Hong-sheng Tan,Hua Zhou,Yuan-zhi Lao,Hong-xi Xu,
来源：中国药理学报（英文版） 年份：2020
Metastasis causes the main lethality in esophageal cancer patient.Garcinol,a natural compound extracted from Gambogic genera,is a histone acetyltransferase (HAT...
[期刊论文] 作者：Man Wu,Yuan-zhi Lao,Hong-sheng Tan,Guang Lu,Yi Ren,Zhao-qing Zheng,Juan Yi,Wen-wei Fu,Han-ming Shen,Hong-xi,
来源：中国药理学报（英文版） 年份：2019
Lysosomes are the terminal organelles of the autophagic-endocytic pathway and play a key role in the degradation of autophagic contents.We previously reported t...
,Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cell
[期刊论文] 作者：Shi-long Jiang,Yi-di Guan,Xi-sha Chen,Peng Ge,Xin-luan Wang,Yuan-zhi Lao,Song-shu Xiao,Yi Zhang,Jin-ming,
来源：中国药理学报（英文版） 年份：2019
Autophagy,a form of cellular self-digestion by lysosome,is associated with various disease processes including cancers,and modulating autophagy has shown promis...
Garciesculenxanthone B induces PINK1-Parkin-mediated mitophagy and prevents ischemia-reperfusion bra
[期刊论文] 作者：Man Wu,Guang Lu,Yuan-zhi Lao,Hong Zhang,Dan Zheng,Zhao-qing Zheng,Juan Yi,Qian Xiang,Li-ming Wang,Hong-sheng,
来源：中国药理学报（英文版） 年份：2021
Mitophagy is a selective form of autophagy involving the removal of damaged mitochondria via the autophagy-lysosome pathway.PINK1-Parkin-mediated mitophagy is o...
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