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Analysis of KRAS/NRAS mutations in PEAK: A randomized phase Ⅱ study of FOLFOX6 plus panitumumab (pma
[会议论文] 作者：Hua Yu,Kelly S.Oliner,William Y.Go,Lee Schwartzberg,Fernando Rivera,Meinolf Karthaus,Gianpiero Fasola,
来源：第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 年份：2013
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Analysis of KRAS/NRAS mutations in PEAK: A randomized phase Ⅱ study of FOLFOX6 plus panitumumab (pma
[会议论文] 作者：Lee Schwartzberg,Fernando Rivera,Meinolf Karthaus,Gianpiero Fasola,Jean-Luc Canon,Hua Yu,Kelly S.Oliner,
来源：第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 年份：2013
目的: PEAK estimated the tx effect of FOLFOX6 with pmab or bev in 1st-line WT KRAS mCRC.The PRIME study showed significantly improved progression free survival (PFS) and overall survival (OS) with pmab+...
Tumor MET Expression by Immunohistochemistry (IHC) in Chinese Patients With Advanced Gastric or Gast
[会议论文] 作者：Zhi Peng,Zhongwu Li,Jing Gao,Ming Lu,Jifang Gong,Kelly S.Oliner,Yong-jiang Hei,Hui Zhou,Lin Shen,
来源：第十七届全国临床肿瘤学大会暨2014年CSCO学术年会 年份：2014
Objective: Gastric cancer accounts for ＞325,000 deaths in China annually.The MET receptor and its ligand hepatocyte growth factor are promising targets in G/GEJ cancer.Our objective was to evaluate ov...
Comprehensive analysis of KRAS and NRAS mutations as predictive biomarkers for single agent panitumu
[会议论文] 作者：Jean-Luc Van Laethem,ThierryAndre,Marc Peeters,Ying Tian,Roger Sidhu,Kelly S.Oliner,Scott D.Patterson,
来源：第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 年份：2013
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Comprehensive analysis of KRAS and NRAS mutations as predictive biomarkers for single agent panitumu
[会议论文] 作者：Salvatore Siena,Eric Van Cutsem,Yves Humblet,Jean-Luc Van Laethem,ThierryAndre,Ying Tian,Roger Sidhu,Kelly S.Oliner,
来源：第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 年份：2013
目的: An exploratory biomarker analysis of the phase 3 randomized,monotherapy 20020408 study of pmab vs.best supportive care (BSC) demonstrated that mutations in KRAS exon 3 and NRAS exons 2 and 3 appea...
Analysis of KRAS/NRAS and BRAF Mutations in the Phase 3 PRIME Study of Panitumumab+FOLFOX4 vs.FOLFOX
[会议论文] 作者：Kelly S.Oliner,Jean-Yves Douillard,Salvatore Siena,Josep Tabernero,Ronald Burkes,Mario Barugel,Yves Humblet,
来源：第十六届全国临床肿瘤学大会暨2013年CSCO学术年会 年份：2013
Background: Analysis of a phase 3 panitumumab monotherapy study suggested that KRAS and NRAS mutations beyond KRAS exon 2 may be predictive of panitumumab efficacy (Peeters M,et al.Clin Cancer Res 201...
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