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[会议论文] 作者：Dale THURMAN,
来源：2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份：2013
This presentation will cover the most travelled path to becoming a toxicologic pathologist in North America.We will start the journey at the undergraduate level and proceed through graduate studies, b...
Evaluation of human monoclonal antibody toxicity,toxicokinetics and immunogenicity in cynomolgus mon
[期刊论文] 作者：YU Hong,Patricia RYAN,LIANG Mei-na,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,QIAO Jun-wen,REN Jin,,
来源：中国药理学与毒理学杂志 年份：2013
OBJECTIVE The aim of this study was to characterize the toxicity of the antibody and in particular,the exposure-response relationship of the immune-mediated tox...
Evaluation of human monoclonal antibody toxicity, toxicokinetics and immunogenicity in cynomolgus mo
[会议论文] 作者：YU Hong,Patricia RYAN,LIANG Mei-na,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,QIAO Jun-wen,REN Jin,
来源：2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份：2013
OBJECTIVE The aim of this study was to characterize the toxicity of the antibody and in particular, the exposure-response relationship of the immune-mediated toxicity between these two dose regimens.M...
Evaluation of cisplatin-induced toxicity in cynomolgus macaques including assessment of potential bi
[期刊论文] 作者：YU Hong,Sonya GALES,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,QIAO Jun-wen,REN Jin,CHEN Ya-fei,Russell,
来源：中国药理学与毒理学杂志 年份：2013
OBJECTIVE Cisplatin-induced nephrotoxicity has been characterized previously in animals and humans.Two studies were conducted in cynomolgus macaques to assess t...
Evaluation of cisplatin-induced toxicity in cynomolgus macaques including assessment of potential bi
[会议论文] 作者：YU Hong,Lew KINTER,Nigel BARRASS,Sonya GALES,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,QIAO Jun-wen,REN,
来源：2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份：2013
OBJECTIVE Cisplatin-induced nephrotoxicity has been characterized previously in animals and humans.Two studies were conducted in cynomolgus macaques to assess the nephrotoxicity of cisplatin and to co...
Evaluation of imipenem toxicity in cynomolgus macaques including assessment of biomarkers of renal d
[期刊论文] 作者：YU Hong,Sonya GALES,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,HU Li-ping,QIAO Jun-wen,REN Jin,CHEN Ya-fei,
来源：中国药理学与毒理学杂志 年份：2013
OBJECTIVE To assess the nephrotoxicity of imipenem and to correlate the pathogenesis of lesions in the kidney with changes in urinary biomarkers of kidney toxic...
[期刊论文] 作者：YU Hong,Nigel BARRASS,Sonya GALES,Eva LENZ,Dan WESTON,Ian WILSONB,Tony PARRY,Helen POWELL,Dale THURMAN,
来源：中国药理学与毒理学杂志 年份：2013
Paracetamol(acetominophen,APAP) was administered orally in a rising dose protocol to 2 male and 2 female Cynomolgus monkeys to determine the Maximum Tolerated d...
Evaluation of imipenem toxicity in cynomolgus macaques including assessment of biomarkers of renal d
[会议论文] 作者：YU Hong,Russell BIALECKI,Lew KINTER,Nigel BARRASS,Sonya GALES,ZHENG Wei-jun,QIN Qiu-ping,Dale THURMAN,
来源：2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份：2013
OBJECTIVE To assess the nephrotoxicity of imipenem and to correlate the pathogenesis of lesions in the kidney with changes in urinary biomarkers of kidney toxicity.METHODS Study #1, 11 monkeys (2-3/se...
[会议论文] 作者：Qiu-ping,REN Jin,Nigel BARRASS,Sonya GALES,Eva LENZ,Dan WESTON,Ian WILSONB,Tony PARRY,Helen POWELL,Dale THURMAN,
来源：2013年(第三届)中国药物毒理学年会暨药物非临床安全性评价研究论坛 年份：2013
Paracetamol (acetominophen, APAP) was administered orally in a rising dose protocol to 2 male and 2 female Cynomolgus monkeys to determine the Maximum Tolerated dose (MTD) for subsequent toxicology in...
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