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[期刊论文] 作者：徐蓓,DU Guan-Hua,
来源：中国药理学与毒理学杂志 年份：2004
神经系统毒性反应是药物常见的毒性反应.神经系统对外源性和内源性毒性物质的攻击都十分敏感,因而毒性作用的结果也可能较其他系统更为严重.神经毒性的体外评价主要用于药物...
Lectin-like oxidized low-density lipoprotein receptor-1: protein,ligands, expression and pathophysio
[期刊论文] 作者：CHEN Xiu-ping,DU Guan-hua,
来源：中华医学杂志（英文版） 年份：2007
Objective To review the recent research progress in lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1)including its protein, ligands, expression an...
Lectin-like oxidized low-density lipoprotein receptor-1: protein,ligands, expression and pathophysio
[期刊论文] 作者：CHEN Xiu-ping,DU Guan-hua,
来源：中华医学杂志英文版 年份：2007
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[期刊论文] 作者：CHEN Ying,SUN Lan,DU Guan-hua,,
来源：中国药理学与毒理学杂志 年份：2016
Vascular remodeling,which can be found in atherosclerosis,restenosis after angioplasty,hypertension,and some other frequent and serious chronic diseases.Smooth...
[期刊论文] 作者：徐庆荣,李娜,DU Guan-hua,
来源：中药新药与临床药理 年份：2001
目的：通过对牛黄千金散的消炎、镇痛、免疫抑制作用的研究 ，探讨牛黄千金散的药理作用，为临床应用提供理论依据。方法：抗 炎作用应用大白鼠足趾肿胀法、小白鼠耳廓肿胀法；镇痛作用......
[会议论文] 作者：Du Guan-hua,Fang Lian-hua,Gong Li-li,
来源：2012年中美临床和转化医学国际论坛心脑血管病分会论坛(延吉)暨第十二届全国心血管药理学术会议和中俄药理国际研讨会 年份：2012
...
[会议论文] 作者：Xie Tao,Lu Yang,Du Guan-hua,Meng Fan-rui,
来源：The 6th China-Russia International Conference on Medicine(第六 年份：2014
...
[会议论文] 作者：Xie Tao,Meng Fan-rui,Lu Yang,Du Guan-hua,
来源：The 6th China-Russia International Conference on Medicine(第六 年份：2014
Aim: Rhein (4,5-dihydroxyanthraquinone-2-carboxylicacid; 1,8-dihydroxy-3-carboxyanthraquinone) is a major constituent in the rhizome of rhubarb, which has broad pharmacological effects and been widely...
Salvianolic acid A prevents MCAO/R-induced apoptosis through inhibiting PI3K/Akt/GSK3β-mediated sign
[会议论文] 作者：SONG Jun-ke,ZHANG Wen,ZHANG Xue,DU Guan-hua,
来源：中国药理学会第十三次全国学术大会 年份：2015
Aim Middle cerebral artery occlusion/reperfusion (MCAO/R) is a widely used animal model for cerebral ischemiareperfusion injury, which causes great harm to human health.Salvianolic acid A (SalA) from...
[会议论文] 作者：LIU Ai-lin,WANG Hai-di,YANG Fan,DU Guan-Hua,
来源：中国药理学会第十一次全国学术会议 年份：2011
Three stilbenoids with high influenza neuraminidase (NA) inhibition were discovered through high throughput screening.In order to primarily study their structure-activity relationship (SAR), eight sti...
Combination Therapy of Actinomycin D and Cisplatin Achieved Stronger Cytotoxicity via Increasing PUM
[会议论文] 作者：WANG Lin,XU Huan-li,YANG Sheng-qian,DU Guan-hua,
来源：中国药理学会第十三次全国学术大会 年份：2015
Aim To study the synergistic effect and mechanism of actinomycin D to the anticancer activity of cisplatin on KB cells.Methods Cytotoxicity of actinomycin D on KB cells was evaluated by MTT and LDH As...
[会议论文] 作者：ZHANG Li,CHENG Xin-rui,CHEN Ruo-yun,DU Guan-hua,
来源：中国药理学会第十一次全国学术会议 年份：2011
OBJECTIVE To investigate the protective effects of Naodesheng Effective Composite (NEC) on PC12 cells apoptosis induced by H2O2 and mitochondria injury induced by Fe2 +-cysteine system.METHODS To stud...
Involvement of mitochondrial apoptotic pathway and MAPKs/NF-κB inflammatory pathway in the neuroprot
[期刊论文] 作者：GONG Wen-Xia,ZHOU Yu-Zhi,QIN Xue-Mei,DU Guan-Hua,
来源：中国天然药物 年份：2019
Atractylenolide Ⅲ (ATL-Ⅲ),a sesquiterpene compound isolated from Rhizoma Atractylodis Macrocephalae,has revealed a number of pharmacological properties including anti-inflammatory,anti-cancer activity,and neuroprotective effect.Thisstudy ......
Inhibition of chemokine-like factor 1 improves blood-brain barrier dysfunction in rats following foc
[会议论文] 作者：KONG Ling-lei,DU Guan-hua,HU Jin-feng,YUAN Yu-he,CHEN Nai-hong,
来源：中国药理学会第十四次全国学术大会暨施维雅优秀青年药理学工作者奖20周年学术论坛 年份：2016
OBJECTIVE To investigate the role of chemokine-like factor 1 (CKLF1), a novel C-C chemokine, on brain-blood barrier(BBB) integrity in rat focal cerebral isc...
[会议论文] 作者：CHEN Yu-cai,YUAN Tian-yi,ZHANG Hui-fang,FANG Lian-hua,DU Guan-hua,,
来源：中国药理学与毒理学杂志 年份：2016
OBJECTIVE The current therapeutic approaches have a limited effect on the dysregulated pulmonary vascular remodeling,which is characteristic of pulmonary arteri...
[期刊论文] 作者：ZHAO Yan,CHU Xiao,PANG Xiao-Bin,WANG Shao-Hua,DU Guan-Hua,,
来源：Chinese Journal of Natural Medicines 年份：2015
The present study was designed to investigate the antithrombotic effects and underlying mechanisms of the effective components group(ECG) of Xiaoshuantongluo re...
[期刊论文] 作者：LI Ai-Ping,LI Zhen-Yu,QU Ting-Li,QIN Xue-Mei,DU Guan-Hua,,
来源：Chinese Journal of Natural Medicines 年份：2017
Astragali Radix(AR) is one of the most popular herbal medicines in traditional Chinese medicine(TCM). Wild AR is believed to be of high quality, and substitutio...
Inhibition of chemokine-like factor 1 improves bloodbrain barrier dysfunction in rats following foca
[期刊论文] 作者：KONG Ling-lei,HU Jin-feng,YUAN Yu-he,CHEN Nai-hong,DU Guan-hua,,
来源：中国药理学与毒理学杂志 年份：2016
OBJECTIVE To investigate the role of chemokine-like factor 1(CKLF1),a novel C-C chemokine,on brain-blood barrier(BBB)integrity in rat focal cerebral ischemia an...
Inhibition of chemokine-like factor 1 improves blood-brain barrier dysfunction in rats following foc
[会议论文] 作者：KONG Ling-lei,HU Jin-feng,YUAN Yu-he,CHEN Nai-hong,DU Guan-hua,
来源：中国药理学会第十四次全国学术大会暨施维雅优秀青年药理学工作者奖20周年学术论坛 年份：2016
OBJECTIVE To investigate the role of chemokine-like factor 1 (CKLF1), a novel C-C chemokine, on brain-blood barrier(BBB) integrity in rat focal cerebral ischemia and reperfusion model....
1H NMR based metabolic profiling and differentiation of Astragali Radix from different regions of Ch
[会议论文] 作者：LI Ai-ping,LI Zhen-yu,SUN Hai-feng,QIN Xue-mei,DU Guan-hua,
来源：第一届《药学学报》药学前沿论坛暨2015年中国药学会中药与天然药物专业委员会会议 年份：2015
Astragali Radix(AR)is one of the most popular herbal medicines in Traditional Chinese Medicine(TCM).Wild AR is believed to be of higher quality,and the adulteration of cultivated AR is frequently enco...
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