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[期刊论文] 作者：Yu-jia XU,Li-jie REN,Zu-bin ZHANG,Xin XU,Bi-yin CAO,Ke-sheng DAI,Li ZHU,Qi FANG,
来源：中国药理学报（英文版） 年份：2017
The signal transducer and activator of transcription 3 (STAT3) plays a critical role in platelet functions.This study sought to understand the effects of the ST...
[期刊论文] 作者：Tong Sun,Yu-jia Xu,Shuo-yi Jiang,Zhuan Xu,Bi-yin Cao,Gautam Sethi,Yuan-ying Zeng,Yan Kong,Xin-liang Mao,
来源：中国药理学报（英文版） 年份：2021
Recent studies show that the expression of CCND1,a key factor in cell cycle control,is increased following the progress and deteriotation of glioma and predicts poor outcomes.On the other hand,dysregulated deubiquitinase USP10 also predicts......
TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lun
[期刊论文] 作者：Yuan-ming He,Xiu-min Zhou,Shuo-yi Jiang,Zu-bin Zhang,Bi-yin Cao,Jin-bao Liu,Yuan-ying Zeng,Jun Zhao,Xin-liang,
来源：中国药理学报（英文版） 年份：2022
The PTEN/AKT/mTOR signaling pathway is frequently dysregulated in non-small cell lung cancer(NSCLC),but the mechanisms are not well-understood.The present study found that the ubiquitin ligase TRIM25 is highly expressed in NSCLC tissues and......
,RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiqu
[期刊论文] 作者：Ying Ren,Xin Xu,Chen-yu Mao,Kun-kun Han,Yu-jia Xu,Bi-yin Cao,Zu-bin Zhang,Gautam Sethi,Xiao-wen Tang,,
来源：中国药理学报（英文版） 年份：2020
RNF6,a RING-type ubiquitin ligase,has been identified as an oncogene in various cancers but its role in multiple myeloma (MM) remains elusive.In the present stu...
[期刊论文] 作者：Xue-han Chen,Yu-jia Xu,Xiao-ge Wang,Peng Lin,Bi-yin Cao,Yuan-ying Zeng,Qi Wang,Zu-bin Zhang,Xin-liang,
来源：中国药理学报（英文版） 年份：2019
c-Maf is a critical oncogenic transcription factor that contributes to myelomagenesis.Our previous studies demonstrated that the deubiquitinase USP5 stabilizes...
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