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目的观察补阳还五汤对脑胶质瘤病人放疗期间认知功能及血清S100β的影响。方法对照组30例,行标准治疗:术后放疗加化疗;治疗组30例,采用放疗加化疗加补阳还五汤治疗。结果 KPS评分及认知功能评分治疗组优于对照组(P<0.05),血清S100β(P<0.05)。结论补阳还五汤显著提高胶质瘤患者放疗期间的认知功能,具有确切的神经保护作用。
Objective To observe the effect of Buyang Huanwu Decoction on cognitive function and serum S100β in patients with glioma during radiotherapy. Methods Control group of 30 patients underwent standard treatment: postoperative radiotherapy and chemotherapy; treatment group of 30 patients treated with radiotherapy and chemotherapy plus Buyanghuanwu Tang treatment. Results KPS score and cognitive function score in the treatment group were better than those in the control group (P <0.05), serum S100β (P <0.05). Conclusion Buyang Huanwu Decoction significantly improves the cognitive function of patients with glioma during radiotherapy and has definite neuroprotective effect.