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免疫机制本文简略地复习了目前关于人疟获得性免疫机制的知识。[吞噬作用] 网状内皮系统(RES)的巨噬细胞的吞噬作用是人体疟疾感染的一个突出特征。在脾、肝和骨髓,以及少数其它器官,这些细胞被证明能够吞噬细胞内的和细胞外的寄生虫、色素和疟原虫碎片。Taliaferro和他的同事们的详细的研究指出,在鸟及猿疟中,在未免疫的动物体内,吞噬寄生虫的作用开始是迟钝的,当动物获得免疫力时,吞噬能力显著增加,可能是通过特异的调理素抗体的中介。脾脏的巨噬细胞的吞噬作用始终表现得比肝和骨髓的巨噬细胞活跃。推测人体内的
Immune Mechanisms This article briefly reviews the current knowledge about the acquired immune mechanisms of human malaria. [Phagocytosis] The phagocytosis of macrophages of the reticuloendothelial system (RES) is a prominent feature of human malaria infection. In the spleen, liver and bone marrow, and a handful of other organs, these cells have been shown to be capable of phagocytizing both intracellular and extracellular parasites, pigments and fragments of malaria parasites. A detailed study by Taliaferro and colleagues points out that in birds and ape-malaria the role of phagocytosis parasites begins to be dull in unimmunized animals, with a significant increase in phagocytosis when animals gain immunity, possibly Mediated by specific opsin antibodies. The phagocytosis of spleen macrophages has always been more active than that of macrophages in liver and bone marrow. Presumably in the human body