论文部分内容阅读
目的探讨适应老年癌症患者生理特点，调整硫酸吗啡控释片给药剂量和给药方法，避免不良反应，达到最佳止痛效果。方法30例晚期癌症患者，口服或肛塞硫酸吗啡控释片，分10mg每12小时给药一次。以后根据镇痛效果按20mg／每日的追加剂量进行调整，直到达到最适剂量。结果中度以上疼痛缓解率为93．3％。不良反应以便秘、恶心、呕吐及嗜睡为最多见。结论老年人个体用药剂量小于一般人群。直肠给药有助减轻不良反应。
Objective To explore the physiological characteristics of elderly patients with cancer, adjust the dosage and method of administration of morphine sulfate controlled release tablets, avoid adverse reactions, and achieve the best analgesic effect. Methods 30 patients with advanced cancer were treated with oral or anal morphine sulphate controlled-release tablets, and 10 mg every 12 hours. Later, according to the analgesic effect, an additional dose of 20 mg/day was adjusted until the optimal dose was reached. Results The moderate pain relief rate was 93.3%. Adverse reactions such as cough, nausea, vomiting and lethargy are the most common. Conclusion The dosage of the elderly individuals is less than the general population. Rectal administration helps to reduce adverse reactions.