支气管哮喘(以下简称哮喘)是一种由多种炎性细胞及细胞组分共同参与的慢性呼吸道炎性疾患。其发病机制迄今尚未完全清楚,气道炎症、免疫与变态反应、气道高反应性、神经调控、遗传因素及骨髓参与机制及其相互作用等与哮喘的发病关系密切。近年来,研究发现大环内酯类抗生素(MA) Bronchial asthma (hereinafter referred to as asthma) is a chronic inflammatory disease of the respiratory tract that is composed of a variety of inflammatory cells and cellular components. Its pathogenesis has not yet been completely understood. Airway inflammation, immune and allergic reactions, airway hyperresponsiveness, neurological regulation, genetic factors and bone marrow involvement mechanisms and their interactions are closely related to the pathogenesis of asthma. In recent years, the study found that macrolide antibiotics (MA)