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近五年来我国药物化学研究工作无論是在数量上和质量上都有很大的增长和提高,寻找药物的重点是集中在危害人民健康最严重的疾病如肿瘤、心血管系統疾病、寄生虫病等,此外对于治疗神經系統疾病的药物、抗菌药、直接应用于农业的杀虫剂以及中药等等,亦給予很大的重視。因此,五年来药物化学研究工作对保証人民的身体健康、药物的生产以及祖国医学的整理等各方面都作出了一定的成績。現就它的两个方面即合成药物和天然药物分別叙述如下。合成药物一、抗腫瘤药物的研究在这方面虽大部分工作仍集中于細胞毒和抗代謝类化合物,但有不少工作是超越了上述范围,企图开辟一条新的道路。
In the past five years, the research on pharmaceutical chemistry in China has grown and improved both in quantity and quality. The focus of drug search is on the most serious diseases that endanger people’s health, such as cancer, cardiovascular diseases, and parasites. Diseases, etc., in addition to the treatment of nervous system diseases drugs, antibacterial drugs, pesticides applied directly to agriculture and Chinese medicine, etc., also give great importance. Therefore, over the past five years, the research on medicinal chemistry has made certain achievements in ensuring the people’s health, drug production, and the organization of the motherland medicine. Two aspects of it, synthetic drugs and natural drugs, are described below. Synthetic drugs 1. Research on anticancer drugs Although most of the work in this area is still focused on cytotoxic and anti-metabolic compounds, there are many tasks that go beyond the above-mentioned scope in an attempt to open up a new path.