昌都县位于西藏高原东部,平均海拔3800m,交通极为不便,居住分散。1988年2～7月,该县约巴乡发生一起斑疹伤寒暴发。全乡344人,发病37人,死亡4人,罹患率10.75％。发病年龄最小8岁,最大62岁,20～40岁发病最多。病程最短20天,最长2个月。发病呈聚集性,37例患者分布在7户中,有1户10人全发病。临床表现为剧烈头痛等明显的神经系统 Chandu County is located in the eastern part of Tibet Plateau, with an average elevation of 3800m, traffic is very inconvenient, living scattered. From February to July 1988, a typhus outbreak occurred in Yoba County, the county. The township, 344 people, the incidence of 37 people, 4 people were killed, the attack rate of 10.75%. The youngest age of 8 years old, up to 62 years old, 20 to 40 years of age the most. The shortest course of 20 days, up to 2 months. The incidence was clustered, 37 patients were distributed in 7 households, 10 households were 10 cases of the full incidence. Clinical manifestations of severe headache and other obvious nervous system