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目的 通过对 4例重度毒鼠强中毒抢救及疗效的观察 ,探讨安定在抢救中的使用剂量问题。方法持续静脉滴注超大剂量安定 ,总量分别达 70 ,1 0 0 ,1 0 0 ,1 2 0mg ,同时予以脱水、利尿、保护脑细胞、维持水电解质及酸碱平衡等综合治疗。结果 安定使用中未出现呼吸抑制等副作用 ,3例痊愈出院 ,1例因脑疝而死亡。结论 持续静脉滴注超大剂量安定 ,尽早控制抽搐 ,是抢救重度毒鼠强中毒成功的关键。
Objective To investigate the efficacy and safety of tetramine poisoning in rats and discuss the dosage of diazepam in the rescue. Methods Continuous intravenous infusion of large doses of diazepam, the total amount of 70, 100, 100, 120mg, at the same time to dehydration, diuretic, protect brain cells, maintaining water and electrolyte and acid-base balance and other comprehensive treatment. The results did not appear stable use of respiratory depression and other side effects, 3 patients were discharged, 1 case died of herniation. Conclusion Continuous intravenous infusion of large doses of diazepam as soon as possible to control seizures is the key to the success of severe poisoning to save rats.