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目的对比封闭负压辅助闭合(vacuum-assisted closure,VAC)技术与传统换药方法对糖尿病足溃疡的临床疗效。方法对46例糖尿病足溃疡患者随机分为VAC治疗组(23例)和对照组(23例),VAC治疗组采用局部清创、控制血糖、抗感染等常规治疗,在其分泌物细菌培养阴性前提下,加行VAC治疗,待创面肉芽填充丰满后行常规换药至伤口愈合。对照组采用常规换药技术,常规清创后,定期换药至伤口愈合。结果 VAC治疗1～3个疗程,患者创面肉芽组织生长新鲜、红润,无感染、水肿、渗出,创面愈合时间(50.4±5.3)d。对照组创面愈合时间(81.1±5.9)d。两组对比差异有统计学意义(P﹤0.01)。结论 VAC治疗糖尿病足溃疡可改善其局部血运,减轻局部水肿,促进创面肉芽组织生长,缩短创面愈合时间。
Objective To compare the clinical effects of vacuum-assisted closure (VAC) and traditional dressing methods on diabetic foot ulcers. Methods 46 patients with diabetic foot ulcer were randomly divided into VAC treatment group (23 cases) and control group (23 cases). VAC treatment group was treated by local debridement, blood glucose control, anti-infection and other routine treatment, in the secretion of bacterial culture negative Under the premise, plus line VAC treatment, until the wound granulation filled with conventional dressing to the wound healing. The control group using conventional dressing technology, routine debridement, regular dressing to the wound healing. Results VAC was treated for 1 to 3 courses. The wound granulation tissue grew freshly, rosy, no infection, edema, exudation and wound healing time (50.4 ± 5.3) d. Control group wound healing time (81.1 ± 5.9) d. The difference between the two groups was statistically significant (P <0.01). Conclusion VAC treatment of diabetic foot ulcer can improve its local blood supply, reduce local edema, promote wound granulation tissue growth, shorten the wound healing time.