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目的探讨在2型糖尿病患者中运用预混门冬胰岛素30及预混人胰岛素30R的治疗作用。方法通过随机对照法将近期到我院治疗的62例2型糖尿病病例均分成两组,对照组31例选择预混人胰岛素30R用药,观察组31例通过预混门冬胰岛素30治疗,连续用药满8周后,研究两组的病情改善情况。结果用药前,两组的FPG、2h PBG和Hb Alc值比较相近,不具统计学意义(P>0.05),用药后,观察组各项指标值相比对照组明显下降,有统计学意义(P<0.05)。两组用药期间均有低血糖出现,但相对而言,观察组的发生率有所降低,有统计学意义(P<0.05)。结论选择预混门冬胰岛素30对2型糖尿病展开治疗,降糖效果相比预混人胰岛素更加理想、安全,适合加强推广。
Objective To investigate the therapeutic effect of using prefixed insulin aspart 30 and pre-mixed insulin 30R in patients with type 2 diabetes mellitus. Methods A total of 62 cases of type 2 diabetes mellitus treated in our hospital were randomly divided into two groups according to a randomized controlled trial. In the control group, 31 patients were treated with 30R insulin-supplemented insulin and 31 patients in the observation group were treated with insulin aspart 30 After eight weeks, study the two groups to improve the situation. Results Before treatment, the values of FPG, 2h PBG and Hb Alc in the two groups were similar and had no statistical significance (P> 0.05). After treatment, the indexes in the observation group decreased significantly compared with the control group (P <0.05). Hypoglycaemia occurred during the two groups, but the incidence of observation group was lower than that of the control group (P <0.05). Conclusion The choice of insulin aspart 30 in the treatment of type 2 diabetes mellitus, hypoglycemic effect compared to pre-mixed insulin is more ideal and safe, suitable for strengthening the promotion.