王某,男性,45岁,口腔双颊侧白色变已6年,初感粗糙似铺一层纱,粗糙面由钱币大小渐扩大至颊侧大部粘膜,1992年活检证实为白斑。同年8月4日局麻下行双颊侧白斑全部切除后植皮,皮片成活良好。1年后植皮区疼痛,易出血,局部僵硬干裂,下唇麻木感。用维生素A,中药治疗无效。86年初开始增长迅速,影响发音,咀嚼。无烟酒嗜好。 Wang, male, 45 years old, had white changes in the cheeks of the oral cavity for 6 years. The initial rough feeling was covered with a layer of gauze. The rough surface gradually expanded from the size of the coin to the mucous membranes on the buccal side. Biopsy was confirmed as white spot in 1992. On August 4th of the same year, the epidermis was excised and all skin grafts on the cheeks were removed. Skin grafts survived well. One year later, the skin graft area was painful, easily bleeding, partially stiff and chapped, and the lower lip numb. With vitamin A, Chinese medicine treatment is ineffective. 86 began to grow rapidly at the beginning of the year, affecting pronunciation and chewing. Non-smoking alcohol hobby.