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病例摘要女,3岁。87年8月11日误饮0.5%复合B 硫酸锌200ml 后,诉咽痛,胸骨后及上腹不适。查体出汗稍多,轻度兴奋,眼睑、下颌渐出现数枚针尖样出血点,心肺肝脾及神经系统无殊。在密切观察下静滴大量维生素C,牛奶一斤频服,口服肌苷液20ml/日,食不含锌的蔬菜,增加大便排泄。并随访一年余无特殊。讨论锌的毒性较小,一般服2克后才会出现毒性反应。成人硫酸锌的致死量约15克;锌的排泄主要通过大便;锌中毒的表现为:1,口腔及消化道粘膜损伤,腹痛腹泻,恶心呕吐,呕、便血,偶可发生急性胰腺炎及穿孔性腹膜炎,重者急性期后可有食道及胃狭窄;2,严重者呼吸急促,瞳孔散大,甚至抽搐、昏迷、休克而
Case Summary Female, 3 years old. August 11, 87, after drinking 0.5% compound B zinc sulfate 200ml, v. Sore throat, chest and upper abdominal discomfort. Sweating slightly more physical examination, mild excitement, eyelids, lower jaw gradually appear several needle-like bleeding, heart and lung, liver and spleen and the nervous system without special. In close observation intravenous infusion of a large number of vitamin C, a pound of milk frequency service, oral glycoside solution 20ml / day, eat vegetables without zinc, increase excretion. And follow-up more than a year without special. Zinc toxicity is less discussed, usually after taking 2 grams of toxic reactions. Adult zinc sulfate lethal dose of about 15 grams; zinc excretion mainly through the stool; zinc poisoning as follows: 1, oral and gastrointestinal mucosal injury, abdominal pain and diarrhea, nausea and vomiting, vomiting, blood in the stool, and even acute pancreatitis and perforation can occur Peritonitis, severe acute phase may have esophageal and gastric stenosis; 2, severe shortness of breath, mydriasis, and even convulsions, coma, shock and