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目的:研究分析还原型谷胱甘肽对早期2型糖尿病肾病氧化应激状态的临床效果。方法:随机选取68例我院2型糖尿病肾病的患者,随机均分为对照组和试验组,对照组接受常规治疗,试验组在对照组基础上应用还原型谷胱甘肽治疗,对比两组相关指标改变。结果:治疗后,试验组患者FPG、PA、尿mALB均明显下降,血清标志物hs-CRP、Hcy也有较大程度上的降低,具有统计学差异(P<0.05)。结论:对于早期2型糖尿病肾病患者,还原型谷胱甘肽能改善患者的氧化应激状态。
OBJECTIVE: To study the clinical effect of reduced glutathione on oxidative stress in patients with type 2 diabetic nephropathy. Methods: A total of 68 patients with type 2 diabetic nephropathy in our hospital were randomly divided into control group and experimental group. The control group received routine treatment. The experimental group was treated with reduced glutathione on the basis of control group. Related indicators change. Results: After treatment, the levels of FPG, PA and urine mALB in the test group decreased significantly, and the serum levels of hs-CRP and Hcy also decreased to a great extent (P <0.05). CONCLUSIONS: Reduced glutathione improves oxidative stress in patients with early stage 2 diabetic nephropathy.