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目的分析青浦区2012年疑似预防接种异常反应(AEFI)的发生情况,评价AEFI监测系统运行状况及预防接种安全性。方法采用描述性流行病学方法对2012年青浦区AEFI监测资料进行分析。结果青浦区2012年共报告AEFI 586例,报告发生率为136.56例/10万剂,其中一般反应581例(99.15%),异常反应4例(0.68%),偶合征1例(0.17%);较多分布在5~8月(49.66%);主要为发热(50.34)和局部红肿(33.96%);报告发生数较多的产品有白百破、流脑A群、流感菌(HIB);报告发生率居前3位的产品是:五联、白百破、流脑A群。586例AEFI中,治愈584例,好转2例。结论青浦区AEFI监测敏感性较高,但仍需要加强AEFI监测工作,应进一步强化预防接种规范操作,注重公众沟通。
Objective To analyze the incidence of suspected AEFI in Qingpu District in 2012 and evaluate the operation status of AEFI monitoring system and vaccination safety. Methods A descriptive epidemiological method was used to analyze the AEFI surveillance data of Qingpu District in 2012. Results A total of 586 AEFI cases were reported in Qingpu District in 2012, with a reported incidence rate of 136.56 cases / 100000 doses. Among them, 581 cases (99.15%) were general reactions, 4 cases (0.68%) were abnormal reactions and 1 case (0.17%) were anomalies. (49.66%) were mainly distributed in the period from May to August. The main causes were fever (50.34) and local redness (33.96%). The top three reported incidence of the product are: five, Bai Bai broken, meningitis A group. 586 cases of AEFI, 584 cases were cured, improved in 2 cases. Conclusion The sensitivity of AEFI surveillance in Qingpu District is high, but the monitoring of AEFI is still needed to be strengthened. Norms and practices of vaccination should be further strengthened and public communication should be emphasized.