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目的总结56例卡介苗所致淋巴结强反应的临床表现,评价局部治疗效果。方法收集2010年1月-2014年5月结核病门诊56例由卡介苗所致淋巴结强反应患儿,根据其临床表现,分别给予热敷、清创引流及敷药等局部治疗,并分析疗效。结果 1)分型:结节未液化型7例,液化型20例,脓肿破溃型23型,术后伤口未愈者6例。2)疗效:7例未液化型经局部热敷,5例结节缩小,2例结节液化;22(20+2)例液化型经穿刺针吸及结节内注射异烟肼,均化脓破溃;45(23+22)例脓肿破溃型经清创引流,利福平外敷,伤口愈合;6例手术后伤口未愈者经清创引流、利福平外敷,伤口愈合。结论新生儿接种卡介苗所致淋巴结强反应临床表现多样,局部治疗效果好。
Objective To summarize the clinical manifestations of 56 cases of BCG-induced strong lymph node reaction and evaluate the effect of local treatment. Methods From January 2010 to May 2014, 56 children with TB-induced strong response to BCG from tuberculosis clinic were treated with topical treatment such as hot compress, debridement and dressing, respectively, according to their clinical manifestations. The curative effect was analyzed. Results 1) Type: nodular non-liquefied type in 7 cases, liquefied type in 20 cases, abscess ruptured type 23, and postoperative wound unhealed in 6 cases. 2) Efficacy: 7 cases of non-liquefied local heat, 5 cases of nodules shrink, 2 cases of nodular liquefaction; 22 (20 +2) cases of liquefied type puncture needle and intranodular injection of isoniazid, Ulceration; 45 (23 +22) cases of abscess rupture by debridement drainage, rifampicin topical, wound healing; 6 cases of wounds after healing hemorrhage by debridement, rifampin topical wound healing. Conclusion Newborns vaccinated with BCG caused by the clinical manifestations of strong response to lymph nodes, local treatment effect is good.