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地肤子(Kochia scoparia的果实)的70％乙醇提取物对复合物48/80(48/80)或5-羟色胺诱致搔痒动作模型有抑制作用,并分离出活性成分齐墩果酸寡糖葡糖甙木鳖子甙Ic,2’-O-β-D-呋喃葡糖基木鳖子甙Ic。此次使用齐墩果酸寡糖葡糖甙,对其构效关系进行了研究。
The 70% ethanol extract of Kochia scoparia (the fruit of Kochia scoparia) inhibited the action model of compound 48/80 (48/80) or serotonin-induced pruritus, and isolated the active ingredient oleanolic acid oligosaccharide Portuguese Sugar glycosides glycosides Ic, 2’-O-β-D-glucopyranose glycosides Ic. The structure-activity relationship of oleanolic acid oligosaccharide glucoside was studied.