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为探讨卵巢恶性肿瘤（ＭＯＴ）与细胞免疫的关系，对４０例ＭＯＴ患者和３０例正常对照（ＮＣ）妇女的Ｔ淋巴细胞亚群和白细胞介素－２（ＩＬ－２）、可溶性白细胞介素－２受体（ｓＩＬ－２Ｒ）进行了同步检测及相关性研究。结果：ＭＯＴ组ＩＬ－２、ＣＤ＋３、ＣＤ＋４、ＣＤ＋４／ＣＤ＋８均低于ＮＣ组，ｓＩＬ－２Ｒ、ＣＤ＋８均高于ＮＣ组（Ｐ＜０．０１～０．００１），其中ＣＤ＋３、ＣＤ＋４、ＣＤ＋４／ＣＤ＋８与ＩＬ－２呈正相关，与ｓＩＬ－２Ｒ呈负相关（Ｐ＜０．０１～０．００１）。提示本病患者Ｔ淋巴细胞免疫功能低下，ＣＤ＋３、ＣＤ＋４、ＣＤ＋４／ＣＤ＋８值的降低与ＩＬ－２活性下降和ｓＩＬ－２Ｒ水平增高有关，它们均可能是本病发生发展的重要因素。
To investigate the relationship between ovarian cancer (MOT) and cellular immunity, T-lymphocyte subsets and interleukin-2 (IL-2), soluble interleukin in 40 women with MOT and 30 women with normal controls (NC) -2 receptors (sIL-2R) were simultaneously detected and correlated. Results: The levels of IL-2, CD+3, CD+4 and CD+4/CD+8 in MOT group were lower than NC group, sIL-2R, CD+8 were higher than NC group (P<0.01-0.001), among which CD+3, CD+4, CD+4/ CD+8 was positively correlated with IL-2 and negatively correlated with sIL-2R (P<0.01-0.001). It is suggested that the immune function of T lymphocytes in patients with this disease is low, and the decrease of CD+3, CD+4, and CD+4/CD+8 levels is related to the decrease of IL-2 activity and the increase of sIL-2R levels. They may be important factors in the development of this disease.