目的:分析百令片联合坎地沙坦对糖尿病肾病患者的临床治疗效果。方法:选择我院2015年6月~2016年6月收治的98例糖尿病肾病作为研究对象,参照抽签法随机分为对照组与观察组,每组各49例。对照组予以坎地沙坦治疗,观察组基于对照组使用百令片治疗,比较两组治疗前后血清胱抑素(Cys-C)、β2微球蛋白(β2-MG)、尿素氮(BUN)、肌酐(Cr)、白细胞介素-6(IL-6)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、血糖、血压水平和不良反应的发生情况。结果:治疗后,两组血清Cys-C、β2-MG、BUN、Cr、IL-6、CRP、TNF-α、血糖和血压水平均较治疗前显著降低,且观察组血清Cys-C、β2-MG、BUN、Cr、IL-6、CRP、TNF-α和血压水平显著低于对照组,差异均具有统计学意义(P<0.05)。结论:百令片联合坎地沙坦治疗可更有效改善糖尿病肾病患者的肾功能、血压和血糖水平,抑制其炎症反应,且安全性较好。 OBJECTIVE: To analyze the clinical effect of Baxter tablets combined with candesartan on patients with diabetic nephropathy. Methods: A total of 98 patients with diabetic nephropathy who were admitted to our hospital from June 2015 to June 2016 were selected as control group and control group according to the random sampling method, 49 cases in each group. The control group was treated with candesartan. The observation group was treated with bergen tablet in the control group. The levels of serum cystatin C, β2 microglobulin, BUN, , Creatinine (Cr), interleukin-6 (IL-6), C-reactive protein (CRP), tumor necrosis factor-α (TNF- α), blood glucose, blood pressure and adverse reactions. Results: The levels of serum Cys-C, β2-MG, BUN, Cr, IL-6, CRP, TNF-α, blood glucose and blood pressure in the two groups were significantly lower than those before treatment The levels of MG, BUN, Cr, IL-6, CRP, TNF-α and blood pressure were significantly lower than those of the control group (P <0.05). Conclusion: The combination of bergen tablet and candesartan can effectively improve the renal function, blood pressure and blood sugar level of diabetic nephropathy patients, inhibit its inflammatory reaction and is safe.