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印度南方15419名半岁至5岁的儿童参加了为期1年的维生素A补充实验,以观察补充维生素A对儿童腹泻、呼吸道感染及生长发育的影响。参加实验者整群随机分为实验组和对照组。实验组儿童每周服8.7μmol(2500 μg)维生素A和46 μmol(20mg)的维生素E,对照组儿童给予46μmol维生素E作为空白对照。实验前后对儿童进行眼科检查和体格测量。实验期间由社区志愿人员每周对儿童发放一次药物,并通过询问母亲记录上周儿童的发病情况。
In South India, 15 419 children, aged from 5 to 5, participated in a one-year vitamin A supplementation experiment to observe the effects of vitamin A supplementation on children’s diarrhea, respiratory infections and growth. Participants in the experimental group were randomly divided into experimental group and control group. The experimental group received 8.7 micromol (2500 μg) vitamin A and 46 micromol (20 mg) vitamin E weekly, while the control group received 46 micromol vitamin E as a blank control. Before and after the experiment on children ophthalmology and physical measurement. During the experiment, community volunteers distributed weekly drugs to children and asked mothers to record the incidence of children last week.