本文报道了1960～1980年间所治疗的10例恶性中线网织细胞增多症,男6女4,男女之比为3:2。年龄22～53岁,平均年龄36岁。临床表现:9例有5个月～8年不等的鼻炎或鼻窦炎前驱期症状,1例为咽部不适症状。活动期均有迅速发展的局部进行性坏死、溃疡,其中6例有溃烂穿孔,10例至就诊前病变活动已2～4月。终末期1例有贫血、持续高烧等衰竭表 This article reports 10 cases of malignant midline reticulocytosis treated between 1960 and 1980 with 6 males and 4 females with a ratio of 3: 2. Aged 22 to 53 years old, average age 36 years old. Clinical manifestations: 9 cases have 5 months to 8 years of rhinitis or sinusitis prodromal symptoms, 1 case of pharyngeal symptoms. During the active phase, there was a rapid development of local progressive necrosis and ulceration, of which 6 cases had ulcerated perforation, and 10 cases had lesions from February to April before their visit. One case of end-stage anemia, persistent fever and other failure table