鼻息肉组织中大量嗜酸性粒细胞浸润是其病理学特征之一,进一步阐明鼻息肉发病机制,是近年来研究的热点问题之一。在组织学水平标记嗜酸性粒细胞的方法主要是常规苏木精-伊红染色法(hematoxylin-eosin,HE),也可采用MGG(May-Grunwald-Giemsa)特殊染色法,根据细胞形态特征,可较准确地辨认组织中的嗜酸性粒细胞。但上述两种染色法均不是特异性地针对嗜酸性粒细胞,其它炎性细胞和组织结构亦可着色,当细胞形态不典型时,不易将嗜酸性粒细胞与其它炎性细胞相区别,这对于病理诊断经验并不丰富的耳鼻咽喉头颈外科医师尤为困难。我们在以往的研 Nasal polyps in a large number of eosinophilic infiltration is one of its pathological features, to further clarify the pathogenesis of nasal polyps, is one of the hot issues in recent years. Histologically marked eosinophils mainly by conventional hematoxylin-eosin (HE), or MGG (May-Grunwald-Giemsa) special staining, according to cell morphology, Eosinophils in tissues can be more accurately identified. However, the above two staining methods are not specific for eosinophils, other inflammatory cells and tissues can also be colored, when the cell morphology is not typical, it is not easy to distinguish eosinophils and other inflammatory cells, which It is particularly difficult for otolaryngology and head and neck surgeons who are not rich in pathological diagnosis. We studied in the past