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组织细胞(Histiocyte,HC)或称巨噬细胞是具有多种功能的免疫活性细胞,在宿主抗肿瘤免疫中具有重要作用。淋巴瘤组织中HC反应的数量及其分布与肿瘤组织学类型和预后的关系已逐渐受到人们的重视,但认识仍不一致。近年来,随着免疫组织化学研究的深入,HC标记的新技术不断涌现,特别是单克隆抗体出现,为HC的研究带来了美好前景。本文就此概括作一综述。一、HC的分类 HC的分类和命名相当混乱,目前尚未统一。通常把HC再分为HC和巨噬细胞,后
Histiocytes (HCs), or macrophages, are immunocompetent cells that have multiple functions and play an important role in host anti-tumor immunity. The relationship between the number and distribution of HC in lymphatic tissues and tumor histological type and prognosis has gradually been taken seriously, but the understanding is still not consistent. In recent years, with the further research of immunohistochemistry, new technologies of HC labeling are emerging, especially the emergence of monoclonal antibodies, which brings great prospect for HC research. This article summarizes this summary. First, the classification of HC HC classification and naming quite chaotic, not yet unified. HC is usually subdivided into HC and macrophages, later