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目的 研究数字连接试验 (NCT)的影响因素及其对亚临床肝性脑病 (SHE)的诊断价值。方法 对 45 0例正常人进行NCT检测 ,探讨影响因素并定出正常参考值范围 ,与智力检测 (IQ)、脑诱发电位 (EP)检查同时应用于 40例肝硬化患者 ,研究其应用价值。结果 (1)NCT值受年龄及文化程度影响 (P <0 0 0 1) ;(2 )肝硬化患者NCT异常率为 30 % (12 / 40 ) ,低于IQ异常率的 5 8% (2 3/ 40 ) (P <0 0 1) ;(3)IQ检查中的木块图、图片排列、图形拼凑及NCT 4种方法检查本组肝硬化患者阳性率为5 3 % ,与全套IQ的阳性率 (5 8% )相比 ,其敏感性为 87% ,特异性为 94%。 (4 )本组病人SHE的检出率为 85 % (34/ 40 )。结论 NCT结果受年龄及文化程度影响 ,单独应用敏感性低。我们推荐采用IQ检查中的木块图、图片排列、图形拼凑及NCT 4种方法代替全套IQ检查 ,用于SHE的临床诊断
Objective To study the influential factors of digital connection test (NCT) and its diagnostic value in subclinical hepatic encephalopathy (SHE). Methods NCT was performed in 45 0 normal subjects. The influencing factors were determined and the normal reference value range was determined. The value of IQ and brain evoked potentials (EP) was also evaluated in 40 patients with cirrhosis. Results NCT was affected by age and educational level (P <0.01). (2) The abnormality rate of NCT in patients with cirrhosis was 30% (12/40), which was lower than 58% (2 (P <0.01); (3) IQ examination of the block map, picture arrangement, patchwork and NCT four kinds of methods to check the positive rate of liver cirrhosis in this group was 53%, and the full set of IQ Compared with the positive rate (58%), the sensitivity was 87% and the specificity was 94%. (4) The detection rate of SHE in this group was 85% (34/40). Conclusion The results of NCT are affected by age and education level, and the sensitivity of the application alone is low. We recommend using the IQ check in the block diagram, picture arrangement, patchwork and NCT 4 methods to replace the full set of IQ check for the clinical diagnosis of SHE