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目的 :比较国产和进口头孢哌酮钠 /舒巴坦钠复方制剂体外抑菌效果。方法 :采用Kirby Bauer法 (纸片琼脂扩散法 ) ,分别将不同批次的国产和进口头孢哌酮钠 /舒巴坦钠复方制剂制成每片含药量 75 μg/ 75 μg的药敏纸片 ,贴于接种试验菌株的M H琼脂平皿上 ,35℃、培养 16～ 18h后测量抑菌圈直径。结果 :国产和进口头孢哌酮钠 /舒巴坦钠对大肠埃希菌、金黄色葡萄球菌、铜绿假单胞菌等 7种细菌抑菌圈大小无明显差别 (P >0 .0 5 )。结论 :国产和进口头孢哌酮钠 /舒巴坦钠对这7种细菌体外抗菌作用相同。
Objective: To compare the in vitro antibacterial activity of domestic and imported cefoperazone sodium / sulbactam sodium. Methods: Kirby Bauer method (paper agar diffusion method), respectively, of different batches of domestic and imported cefoperazone sodium / sulbactam sodium compound drug tablets each containing 75 μg / 75 μg of drug susceptibility paper The diameter of the zone of inhibition was measured on MH agar plates inoculated with test strains at 35 ° C for 16-18 h. Results: Domestic and imported cefoperazone sodium / sulbactam sodium showed no significant difference in the inhibition zone size of seven kinds of bacteria (Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa) (P> 0.05). Conclusion: Domestic and imported cefoperazone sodium / sulbactam sodium have the same antibacterial effect on these 7 kinds of bacteria in vitro.