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目的:探讨对低体重/极低体重儿强化母乳喂养治疗过程中喂养不耐受(IF)、坏死性小肠结肠炎(NEC)发生率的影响。方法:选取新生儿科重症监护室2014年5~11月符合条件实施强化母乳喂养的低体重/极低出生体重儿438例为观察组,2013年10月~2014年4月早产儿配方奶喂养的低体重/极低住院体重儿560例为对照组,对比两组治疗期间喂养不耐受与坏死性小肠结肠炎的发病率并进行加权及卡方检验。结果:实施强化母乳喂养的低体重/极低出生体重儿发生喂养不耐受、坏死性小肠结肠炎的病例数明显低于早产儿配方奶喂养的低体重/极低住院体重儿,差异有统计学意义(P<0.05)。结论:实施强化母乳喂养能够减少低体重/极低出生体重儿院内治疗期间喂养不耐受及NEC的发生,从而缩短了患儿的住院时间,减轻了家属的经济负担。
Objective: To investigate the effects of feeding intolerance (IF) and necrotizing enterocolitis (NEC) during intensive breastfeeding on low birth weight / very low birth weight infants. Methods: 438 cases of low birth weight / very low birth weight who were eligible for intensive breastfeeding from May to November 2014 were selected as the observation group. From October 2013 to April 2014, the infant formula fed 560 cases of low birth weight / very low in-hospital weight children as the control group. The incidence of feeding intolerance and necrotizing enterocolitis during the two groups were compared and weighted and chi-square test was performed. RESULTS: Feeding intolerance, necrotizing enterocolitis in underweight / very low birth weight infants under intensive breastfeeding were significantly lower than those in low infants / very low in-hospital infants fed formula milk from preterm infants, with statistical differences Significance (P <0.05). CONCLUSIONS: Intensive breastfeeding can reduce feeding intolerance and NEC during hospital inpatients with low birth weight / very low birth weight, shorten the hospital stay and reduce the financial burden on families.