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细胞间黏附分子-1(intercellular adhesion molecule,ICAM-1)在肿瘤侵袭转移过程中起重要作用,可溶性ICAM-1(solubleICAM-1,sICAM-1)是细胞膜型ICAM-1经水解脱落而成,其抗原性与ICAM-1相同。本研究通过测定喉癌患者血清中sICAM-1,探讨sICAM-1在喉癌侵袭转移中的生物学作用及临?
Intercellular adhesion molecule-1 (ICAM-1) plays an important role in tumor invasion and metastasis. Soluble ICAM-1 (solubleICAM-1, sICAM-1) is formed by the hydrolysis of ICAM- Its antigenicity and ICAM-1 the same. In this study, sICAM-1 was measured in sera of laryngeal cancer patients to investigate the biological role of sICAM-1 in the invasion and metastasis of laryngeal cancer and its clinical significance.