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重度二尖瓣关闭不全,可显著降低患者的生存时间。二尖瓣关闭不全的治疗包含药物治疗、外科手术治疗和介入治疗。介入治疗提高了不能手术或高危患者的生活质量和临床转归,新型的二尖瓣介入器械也在不断地研发。现对二尖瓣关闭不全的介入治疗进展做一综述。“,”Severe mitral regurgitation ( MR) is associated with decreased survival rates .The treatment of MR includes medication , surgery and transcatheter therapy .Transcatheter therapy improves the quality of life and clinical outcomes in patients with severe MR .New interventional mitral devices continue to be researched and developed .This paper aims to make a comprehensive review about the recent pro-gress in transcatheter therapy of MR .