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1964年发现 A2G 小鼠能耐受对其它小鼠致死剂量的流感病 毒感染，这种特性是从小鼠16号染色体上单一显性等位基因遗 传获得的，因能抵抗副粘病毒(流感)而将其命名为 Mx 基因。 Mx~+细胞经干扰素(IFN)α处理后与 Mx 的差别是多出一条 7．5×10~4的多肽，而且这种蛋白只有在 IFN α/β诱导后产生， 即 Mx 蛋白。人类 Mx 蛋白分为 MxA 和 MxB，MxA 集中于 IFN
In 1964 A2G mice were found to be able to tolerate a lethal dose of influenza virus infection in other mice. This property was inherited from a single dominant allele on mouse chromosome 16 due to resistance to paramyxovirus (influenza) Name it Mx gene. The difference between Mx ~ + cells and Mx after interferon (IFN) α treatment is an extra 7.5 × 10 ~ 4 polypeptide, and this protein is only produced after induction of IFNα / β, namely Mx protein. Human Mx proteins are divided into MxA and MxB and MxA is focused on IFN