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目的总结经单侧鼻腔蝶窦入路切除垂体腺瘤的手术经验及疗效。方法回顾性分析30例垂体腺瘤患者的临床表现及手术方法和经验。结果肿瘤全切除22例,次全切除6例,部分切除2例。术后视力及视野改善者20例,内分泌指标恢复正常者26例。视力及视野无明显改善者2例。2例出现顽固性尿崩3月后治愈。3例脑脊液鼻漏2周后治愈。本组无死亡病例。结论经单侧鼻腔蝶窦入路切除垂体腺瘤手术入路直接、操作时间短、创伤小、并发症少,是较理想的经蝶手术术式。
Objective To summarize the surgical experience and curative effect of resection of pituitary adenoma by unilateral nasal sphenoid sinus approach. Methods Retrospective analysis of 30 cases of pituitary adenoma patients with clinical manifestations and surgical methods and experience. Results Totally 22 patients had complete resection of the tumor, subtotal resection in 6 cases and partial resection in 2 cases. Postoperative visual acuity and visual field in 20 cases, endocrine indicators returned to normal in 26 cases. Visual acuity and visual field no significant improvement in 2 cases. 2 cases of intractable diabetes insipidus cured after 3 months. 3 cases of cerebrospinal fluid rhinorrhea cured after 2 weeks. No deaths in this group. Conclusions Trans-nasal sphenoid sinus approach for pituitary adenoma resection directly, short operation time, less trauma, less complications, is an ideal transsphenoidal surgery.