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目的:探讨呼吸道合胞病毒(RSV)肺炎潮气肺功能的变化及其在临床诊治和评估的作用。方法:对42例RSV肺炎患儿(观察组)急性期、恢复期及25例正常婴幼儿进行潮气肺功能检查,观察潮气流速-容量环各项指标的变化。结果:观察组急性期呼吸频率(RR)升高,每千克体重潮气量(Vt/kg)、吸呼时间比(tI/tE)、达峰时间比(tPTEF/tE)下降,与恢复期比较,RR、tI/tE、tPTEF/tE有统计学差异(p<0.05);恢复期吸呼时间比(tI/tE)、达峰时间比(tPTEF/tE)较正常组显著降低(p<0.05),而呼吸频率(RR)、每千克体重潮气量(Vt/kg)则无明显的差异(p>0.05)。结论:RSV导致的肺炎在急性期时主要表现是小气道通气的受阻,在恢复期时,肺功能仍存在部分异常情况。潮气量是判断患儿肺功能状况、治疗效果的敏感性指标。
Objective: To investigate the changes of respiratory function of respiratory syncytial virus (RSV) pneumonia and its role in clinical diagnosis and evaluation. Methods: Twenty-two children with RSV pneumonia (observation group) were divided into two groups: acute and convalescent, and 25 normal infants with tidal lung function test. The changes of indexes of moisture flow velocity and volume ring were observed. Results: In the acute phase of the observation group, the respiratory rate (RR), the tidal volume per hour (Vt / kg), the ratio of tI / tE and tPTEF / tE decreased, (P <0.05). The recovery time was higher than that of the normal group (p <0.05), and the ratio of tI / tE to tPTEF / tE was significantly lower than that of the normal group ), While respiratory rate (RR), tidal volume per kilogram of body weight (Vt / kg) had no significant difference (p> 0.05). Conclusions: The main manifestation of pneumonia caused by RSV in the acute phase is the obstruction of small airway ventilation. During the convalescent period, there are still some abnormalities in lung function. Tidal volume is to determine the status of children with pulmonary function, the therapeutic effect of sensitivity indicators.